Placenta
Volume 28, Issue 2 , Pages 127-132 , February 2007

Expression of Urocortin in the Extravillous Human Trophoblast at the Implantation Site

  • C.M. Bamberger

      Affiliations

    • Center of Internal Medicine, Department of Gynecopathology, University Hospital Eppendorf, Hamburg 22767, Germany
    • The first two authors contributed equally to this project.
    • ,
  • V. Minas

      Affiliations

    • Laboratory of Human Reproduction, Department of Obstetrics and Gynecology, School of Medicine, University of Crete, Heraklion 71003, Greece
    • The first two authors contributed equally to this project.
    • ,
  • A.-M. Bamberger

      Affiliations

    • Institute of Pathology, Department of Gynecopathology, University Hospital Eppendorf, Hamburg 22767, Germany
    • ,
  • I. Charalampopoulos

      Affiliations

    • Laboratory of Human Reproduction, Department of Obstetrics and Gynecology, School of Medicine, University of Crete, Heraklion 71003, Greece
    • ,
  • Y. Fragouli

      Affiliations

    • Laboratory of Human Reproduction, Department of Obstetrics and Gynecology, School of Medicine, University of Crete, Heraklion 71003, Greece
    • ,
  • H.M. Schulte

      Affiliations

    • Endokrinologikum, Hamburg 22767, Germany
    • ,
  • A. Makrigiannakis

      Affiliations

    • Laboratory of Human Reproduction, Department of Obstetrics and Gynecology, School of Medicine, University of Crete, Heraklion 71003, Greece
    • Corresponding Author InformationCorresponding author. Tel.: +30 2810 392333; fax: +30 2810 394530.

,Accepted 22 March 2006.

References 

  1. Vaughan J, Donaldson C, Bittencourt J, Perrin MH, Lewis K, Sutton S, et al. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor. Nature. 1995;378:287–292
  2. Donaldson CJ, Sutton SW, Perrin MH, Corrigan AZ, Lewis KA, Rivier JE, et al. Cloning and characterization of human urocortin. Endocrinology. 1996;137:2167–2170
  3. Heinrichs SC, Richard D. The role of corticotropin-releasing factor and urocortin in the modulation of ingestive behavior. Neuropeptides. 1999;33:350–359
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  17. Florio P, Cobellis L, Woodman J, Severi FM, Linton EA, Petraglia F. Levels of maternal plasma corticotropin-releasing factor and urocortin during labor. J Soc Gynecol Invest. 2002;9:233–237
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  22. Aboagye-Mathiesen G, Zdravkovic M, Toth FD, Ebbesen P. Effects of human trophoblast-induced interferons on the expression of proto-oncogenes c-fms/CSF-1R, EGF-R and c-erbB2 in invasive and non-invasive trophoblast. Placenta. 1997;18:155–161
  23. Bamberger AM, Minas V, Kalantaridou SN, Radde J, Sadeghian H, Löning T, et al. Corticotropin-releasing hormone modulates human trophoblast invasion through CEACAM-1 regulation. Am J Pathol. 2006;168:141–150
  24. Florio P, Vale W, Petraglia F. Urocortins in human reproduction. Peptides. 2004;25:1751–1757
  25. Reis FM, Luisi S, Florio P, Degrassi A, Petraglia F. Corticotropin-releasing factor, urocortin and endothelin-1 stimulate activin A release from cultured human placental cells. Placenta. 2002;23:522–525
  26. Grammatopoulos DK, Randeva HS, Levine MA, Katsanou ES, Hillhouse EW. Urocortin, but not corticotropin-releasing hormone (CRH), activates the mitogen-activated protein kinase signal transduction pathway in human pregnant myometrium: an effect mediated via R1alpha and R2beta CRH receptor subtypes and stimulation of Gq-proteins. Mol Endocrinol. 2000;14:2076–2091
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  28. Zhao L, Donaldson CJ, Smith GW, Vale WW. The structures of the mouse and human urocortin genes (Ucn and UCN). Genomics. 1998;50:23–33

PII: S0143-4004(06)00094-4

doi: 10.1016/j.placenta.2006.03.013

Placenta
Volume 28, Issue 2 , Pages 127-132 , February 2007

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