Placenta
Volume 29, Issue 5 , Pages 444-453 , May 2008

Seven Placental Transcripts Characterize HELLP-syndrome

  • M. Buimer

      Affiliations

    • Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    • Laboratory of Pediatric Endocrinology, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • R. Keijser

      Affiliations

    • Laboratory of Pediatric Endocrinology, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • J.M. Jebbink

      Affiliations

    • Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    • Laboratory of Pediatric Endocrinology, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • D. Wehkamp

      Affiliations

    • Bioinformatics Laboratory, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • A.H.C. van Kampen

      Affiliations

    • Bioinformatics Laboratory, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • K. Boer

      Affiliations

    • Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • J.A.M. van der Post

      Affiliations

    • Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • C. Ris-Stalpers

      Affiliations

    • Laboratory of Pediatric Endocrinology, Academic Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Academic Medical Center, Laboratory of Pediatric Endocrinology, Room G2-136, PO Box 22660, 1100 DD Amsterdam, The Netherlands. Tel.: +31 20 566 5625; fax: +31 20 691 6396.

,Accepted 11 February 2008.

References 

  1. Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005;365:785–799
  2. Sibai BM. The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing?. Am J Obstet Gynecol. 1990;162:311–316
  3. Ganzevoort W, Rep A, de Vries JI, Bonsel GJ, Wolf H. Prediction of maternal complications and adverse infant outcome at admission for temporizing management of early-onset severe hypertensive disorders of pregnancy. Am J Obstet Gynecol. 2006;195:495–503
  4. Baxter JK, Weinstein L. HELLP syndrome: the state of the art. Obstet Gynecol Surv. 2004;59:838–845
  5. Pijnenborg R, Vercruysse L, Hanssens M. The uterine spiral arteries in human pregnancy: facts and controversies. Placenta. 2006;27:939–958
  6. Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science. 2005;308:1592–1594
  7. Martin JN, Rose CH, Briery CM. Understanding and managing HELLP syndrome: the integral role of aggressive glucocorticoids for mother and child. Am J Obstet Gynecol. 2006;195:914–934
  8. Oudejans CB, van DM, Oosterkamp M, Lachmeijer A, Blankenstein MA. Genetics of preeclampsia: paradigm shifts. Hum Genet. 2007;120:607–612
  9. Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature. 2006;439:353–357
  10. Liu R, Wang X, Chen GY, Dalerba P, Gurney A, Hoey T, et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med. 2007;356:217–226
  11. Velculescu VE, Zhang L, Vogelstein B, Kinzler KW. Serial analysis of gene expression. Science. 1995;270:484–487
  12. Brown MA, Lindheimer MD, de , Swiet M, Van Assche A, Moutquin JM. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy. 2001;20:IX–XIV
  13. Versteeg R, van Schaik BD, van Batenburg MF, Roos M, Monajemi R, Caron H, et al. The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes. Genome Res. 2003;13:1998–2004
  14. Bakker O, Razaki H, de Vijder JJ, Ris-Stalpers C, Wiersinga WM. Expression of the alpha 1, alpha 2, and beta 1 T3-receptor mRNAs in the fasted rat measured using competitive PCR. Biochem Biophys Res Commun. 1998;242:492–496
  15. van Kampen AH, van Schaik BD, Pauws E, Michiels EM, Ruijter JM, Caron HN, et al. USAGE: a web-based approach towards the analysis of SAGE data. Serial Analysis of Gene Expression. Bioinformatics. 2000;16:899–905
  16. Kal AJ, van Zonneveld AJ, Benes V, van den Berg M, Koerkamp MG, Albermann K, et al. Dynamics of gene expression revealed by comparison of serial analysis of gene expression transcript profiles from yeast grown on two different carbon sources. Mol Biol Cell. 1999;10:1859–1872
  17. Alvarez-Silva M, Belo-Diabangouaya P, Salaun J, Dieterlen-Lievre F. Mouse placenta is a major hematopoietic organ. Development. 2003;130:5437–5444
  18. Arngrimsson R, Sigurard S, Frigge ML, Bjarnad ttir RI, Jonsson T, Stefansson H, et al. A genome-wide scan reveals a maternal susceptibility locus for pre-eclampsia on chromosome 2p13. Hum Mol Genet. 1999;8:1799–1805
  19. Lachmeijer AM, Arngrimsson R, Bastiaans EJ, Frigge ML, Pals G, Sigurdardottir S, et al. A genome-wide scan for preeclampsia in the Netherlands. Eur J Hum Genet. 2001;9:758–764
  20. Laivuori H, Lahermo P, Ollikainen V, Widen E, Haiva-Mallinen L, Sundstrom H, et al. Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families. Am J Hum Genet. 2003;72:168–177
  21. Moses EK, Lade JA, Guo G, Wilton AN, Grehan M, Freed K, et al. A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2. Am J Hum Genet. 2000;67:1581–1585
  22. Michiels S, Koscielny S, Hill C. Prediction of cancer outcome with microarrays: a multiple random validation strategy. Lancet. 2005;365:488–492
  23. Hansson SR, Chen Y, Brodszki J, Chen M, Hernandez-Andrade E, Inman JM, et al. Gene expression profiling of human placentas from preeclamptic and normotensive pregnancies. Mol Hum Reprod. 2006;12:169–179
  24. Zhou Y, Bianco K, Huang L, Nien JK, McMaster M, Romero R, et al. Comparative analysis of maternal-fetal interface in preeclampsia and preterm labor. Cell Tissue Res. 2007;329:559–569
  25. Brown MA, Hague WM, Higgins J, Lowe S, McCowan L, Oats J, et al. The detection, investigation and management of hypertension in pregnancy: full consensus statement. Aust N Z J Obstet Gynaecol. 2000;40:139–155
  26. O'Brien JM, Barton JR. Controversies with the diagnosis and management of HELLP syndrome. Clin Obstet Gynecol. 2005;48:460–477
  27. Sibai BM. Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol. 2004;103:981–991
  28. Widmer M, Villar J, Benigni A, Conde-Agudelo A, Karumanchi SA, Lindheimer M. Mapping the theories of preeclampsia and the role of angiogenic factors: a systematic review. Obstet Gynecol. 2007;109:168–180
  29. Zusterzeel PL, Visser W, Peters WH, Merkus HW, Nelen WL, Steegers EA. Polymorphism in the glutathione S-transferase P1 gene and risk for preeclampsia. Obstet Gynecol. 2000;96:50–54
  30. Mise H, Sagawa N, Matsumoto T, Yura S, Nanno H, Itoh H, et al. Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia. J Clin Endocrinol Metab. 1998;83:3225–3229
  31. Cao Y. Angiogenesis modulates adipogenesis and obesity. J Clin Invest. 2007;117:2362–2368
  32. Laivuori H, Gallaher MJ, Collura L, Crombleholme WR, Markovic N, Rajakumar A, et al. Relationships between maternal plasma leptin, placental leptin mRNA and protein in normal pregnancy, pre-eclampsia and intrauterine growth restriction without pre-eclampsia. Mol Hum Reprod. 2006;12:551–556
  33. Smith GC, Stenhouse EJ, Crossley JA, Aitken DA, Cameron AD, Connor JM. Early pregnancy levels of pregnancy-associated plasma protein a and the risk of intrauterine growth restriction, premature birth, preeclampsia, and stillbirth. J Clin Endocrinol Metab. 2002;87:1762–1767
  34. Kanai F, Marignani PA, Sarbassova D, Yagi R, Hall RA, Donowitz M, et al. TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J. 2000;19:6778–6791
  35. Hossain Z, Ali SM, Ko HL, Xu J, Ng CP, Guo K, et al. Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1. Proc Natl Acad Sci U S A. 2007;104:1631–1636
  36. Chung KW, Ferrell RE, Ellis D, Barmada M, Moritz M, Finegold DN, et al. African American hypertensive nephropathy maps to a new locus on chromosome 9q31–q32. Am J Hum Genet. 2003;73:420–429
  37. Roth J, Vogl T, Sorg C, Sunderkotter C. Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules. Trends Immunol. 2003;24:155–158
  38. Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med. 2007;13:1042–1049
  39. Shah DM. Preeclampsia: new insights. Curr Opin Nephrol Hypertens. 2007;16:213–220
  40. Sargent IL, Germain SJ, Sacks GP, Kumar S, Redman CW. Trophoblast deportation and the maternal inflammatory response in pre-eclampsia. J Reprod Immunol. 2003;59:153–160
  41. Winn VD, Haimov-Kochman R, Paquet AC, Yang YJ, Madhusudhan MS, Gormley M, et al. Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term. Endocrinology. 2007;148:1059–1079
  42. Hung TH, Charnock-Jones DS, Skepper JN, Burton GJ. Secretion of tumor necrosis factor-alpha from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: a potential mediator of the inflammatory response in preeclampsia. Am J Pathol. 2004;164:1049–1061
  43. Moffett-King A. Natural killer cells and pregnancy. Nat Rev Immunol. 2002;2:656–663
  44. Roberts JM, Cooper DW. Pathogenesis and genetics of pre-eclampsia. Lancet. 2001;357:53–56
  45. Conde-Agudelo A, Villar J, Lindheimer M. World Health Organization systematic review of screening tests for preeclampsia. Obstet Gynecol. 2004;104:1367–1391

PII: S0143-4004(08)00072-6

doi: 10.1016/j.placenta.2008.02.007

Placenta
Volume 29, Issue 5 , Pages 444-453 , May 2008