Placenta
Volume 29 , Pages 115-120 , October 2008

Morphological Selection of Gametes

,Accepted 5 August 2008.

References 

  1. Benagiano G, Gianaroli L. The new Italian IVF legislation. Reprod Biomed Online. 2004;9:117–125
  2. Rienzi L, Ubaldi F, Iacobelli M, Ferrero S, Minasi MG, Martinez F, et al. Day 3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day 5 blastocyst transfer. Hum Reprod. 2002;17:1852–1855
  3. Rienzi L, Ubaldi F, Iacobelli M, Romano S, Minasi MG, Ferrero S, et al. Significance of morphological attributes of the early embryo. Reprod Biomed Online. 2005;10:669–681
  4. Fisch JD, Rodriguez H, Ross R, Overby G, Sher G. The graduated embryo score (GES) predicts blastocyst formation and pregnancy rate from cleavage-stage embryos. Hum Reprod. 2001;16:1970–1975
  5. Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Vercruyssen M, Barudy-Vasquez J, et al. Elective single day 3 embryo transfer halves the twinning rate without decrease in the ongoing pregnancy rate of an IVF/ICSI programme. Hum Reprod. 2002;17:626–631
  6. Scott L. Pronuclear scoring as a predictor of embryo development. Reprod Biomed Online. 2003;6:201–214
  7. Balaban B, Urman B. Embryo culture as a diagnostic tool. Reprod Biomed Online. 2003;7:671–682
  8. Brown JB. Pituitary control of ovarian function: concepts derived from gonadotropin therapy. Aust N Z J Obstet Gynaecol. 1978;18:46–54
  9. Hughes EG, Fedorkow DM, Daya S, Sagle MA, Van de Koppel P, Collins JA. The routine use of gonadotropin-releasing hormone agonists prior to in vitro fertilization and gamete intrafallopian transfer: a meta-analysis of randomized controlled trials. Fertil Steril. 1992;58:888–896
  10. Beerendonk CC, Van Dop PA, Braat DD, Merkus JM. Ovarian hyperstimulation syndrome: facts and fallacies. Obstet Gynecol Surv. 1998;53:439–449
  11. De Jong D, Macklon NS, Fauser BC. A pilot study involving minimal ovarian stimulation for in vitro fertilization: extending the “follicle-stimulating hormone window” combined with gonadotropin-releasing hormone antagonist cetrorelix. Fertil Steril. 2000;73:1051–1054
  12. Hohmann FP, Macklon NS, Fauser BCJM. A randomized comparison of two ovarian stimulation protocols with gonadotropin-releasing hormone (GnRH) antagonist cotreatment for in vitro fertilization commencing recombinant follicle-stimulating hormone on cycle day 2 or 5 with the standard long GnRH agonist protocol. J Clin Endocrinol Metab. 2003;88:166–173
  13. Heijien EMEW, Macklon NS, Fauser BCJM. What is the most relevant standard of success in assisted reproduction? The next step to improving outcomes of IVF: consider the whole treatment. Hum Reprod. 2004;19(9):1936–1938
  14. Baart EB, Martini E, Eijkemans MJ, Van Opstal D, Beckers NG, Verhoeff A, et al. Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial. Hum Reprod. 2007;4:1–9
  15. Nargund G, Waterstone J, Bland J, Philips Z, Parsons J, Campbell S. Cumulative conception and live birth rates in natural (unstimulated) IVF cycles. Hum Reprod. 2001;16(2):259–262
  16. Ubaldi F, Rienzi L, Ferrero S, Baroni E, Iacobelli M, Sapienza F, et al. Natural in vitro fertilization cycles. Ann N Y Acad Sci. 2004;1034:245–251
  17. Kolibianakis E, Zikopoulos K, Camus M, Tournaye H, Van Steirteghem A, Devroey P. Modified natural cycle for IVF does not offer a realistic chance of parenthood in poor responders with high day 3 FSH levels, as a last resort prior to oocyte donation. Hum Reprod. 2004;19:2545–2549
  18. Pelinck MJ, Knol HM, Vogel NE, Arts EG, Simons AH, Heineman MJ, et al. Cumulative pregnancy rates after sequential treatment with modified natural cycle IVF followed by IVF with controlled ovarian stimulation. Hum Reprod. 2008;23:1808–1814
  19. Out HJ, Mannaerts BM, Driessen SG, Bennink HJ. A prospective, randomized, assessor-blind, multicentre study comparing recombinant follicle-stimulating hormone (Puregon versus Metrodin) in in-vitro fertilization. Hum Reprod. 1995;10:2534–2540
  20. Daya S, Gunby J, Hughes EG, Collins JA, Sagle MA. Follicle-stimulating hormone versus human menopausal gonadotrophin for in vitro fertilization cycles: a meta-analysis. Fertil Steril. 1995;64:347–354
  21. Bergh C, Howles C, Borg K, Hamberger L, Josefsson B, Nilsson L, et al. Recombinant human follicle stimulating hormone (r-hFSH; Gonal-F) versus highly purified urinary FSH (Metrodin HP): results of a randomized comparative study in women undergoing assisted reproductive techniques. Hum Reprod. 1997;10:2133–2139
  22. Agrawal R, Holmes J, Jacobs HS. Recombinant human follicle-stimulating hormone or human menopausal gonadotrophin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis. Fertil Steril. 2000;73:338–343
  23. Daya S. Updated meta-analysis of recombinant follicle-stimulating hormone (FSH) versus urinary FSH for ovarian stimulation in assisted reproduction. Fertil Steril. 2002;77:711–714
  24. AI-Inany H, Aboulghar M, Mansour R, Serour G. Meta-analysis of recombinant versus urinary-derived FSH: an update. Hum Reprod. 2003;18:305–313
  25. Huang FJ, Lan KC, Kung FT, Tsai MY, Chang CY, Huang HW, et al. Human cumulus-free oocyte maturational profile and in vitro developmental potential after stimulation with recombinant versus urinary FSH. Hum Reprod. 2004;19:306–315
  26. Jacob S, Drudy L, Conroy R, Harrison RF. Outcome from consecutive in-vitro fertilization/intracytoplasmic sperm injection attempts in the final group treated with urinary gonadotrophins and the first group treated with recombinant follicle stimulating hormone. Hum Reprod. 1998;13:1783–1787
  27. Smitz J, Andersen AN, Devroey P, Arce JC, MERIT Group . Endocrine profile in serum and follicular fluid differs after ovarian stimulation with HP-hMG or recombinant FSH in IVF patients. Hum Reprod. 2007;22:676–687
  28. Van Blerkom J. The influence of intrinsic and extrinsic factors on the developmental potential and chromosomal normality of the human oocyte. J Soc Gynecol Investig. 1996;3:3–11
  29. Van Blerkom J, Antezak M, Schrader R. The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. Hum Reprod. 1997;12:1047–1055
  30. Battaglia C, Genazzani AD, Regnani G, Primavera MR, Petraglia F, Volpe A. Perifollicular Doppler flow and follicular fluid vascular endothelial growth factor concentrations in poor responders. Fertil Steril. 2000;74:809–812
  31. Van Blerkom J. Epigenetic influences on oocyte developmental competence: perifollicular vascularity and intrafollicular oxygen. J Assist Reprod Genet. 1998;15:226–234
  32. Coulam CB, Goodman C, Rinehart JS. Colour Doppler indices of follicular blood flow as predictors of pregnancy after in vitro fertilization and embryo transfer. Hum Reprod. 1999;14:1979–1982
  33. Chui DK, Pugh ND, Walker SM, Gregory L, Shaw RW. Follicular vascularity – the predictive value of transvaginal power Doppler ultrasonography in an in vitro fertilization programme: a preliminary study. Hum Reprod. 1997;12:191–196
  34. Bhal PS, Pugh ND, Chui DK, Gregory L, Walker SM, Shaw RW. The use of transvaginal power Doppler ultrasonography to evaluate the relationship between perifollicular vascularity and outcome in in vitro fertilization treatment cycles. Hum Reprod. 1999;14:939–945
  35. Bhal PS, Pugh ND, Gregory L, O'Brien S, Shaw RW. Perifollicular vascularity as a potential variable affecting outcome in stimulated intrauterine insemination treatment cycles: a study using transvaginal power Doppler. Hum Reprod. 2001;16:1682–1689
  36. Borini A, Maccolini A, Tallarini A, Bonu MA, Sciajno R, Flamigni C. Perifollicular vascularity and its relationship with oocyte maturity and IVF outcome. Ann N Y Acad Sci. 2001;943:64–67
  37. Ragni G, Anselmino M, Nicolosi AE, Brambilla ME, Calanna G, Somigliana E. Follicular vascularity is not predictive of pregnancy outcome in mild controlled ovarian stimulation and IUI cycles. Hum Reprod. 2007;22:210–214
  38. Huey S, Abuhamad A, Barroso G, Hsu MI, Kolm P, Mayer J, et al. Perifollicular blood flow Doppler indices, but not follicular pO2, pCO2, or pH, predict oocyte developmental competence in in vitro fertilization. Fertil Steril. 1999;72:707–712
  39. Kan A, Ng EH, Yeung WS, Ho PC. Perifollicular vascularity in poor ovarian responders during IVF. Hum Reprod. 2006;21:1539–1544
  40. Ng EH, Tang OS, Chan CC, Ho PC. Ovarian stromal vascularity is not predictive of ovarian response and pregnancy. Reprod Biomed Online. 2006;12:43–49
  41. Palomba S, Russo T, Falbo A. Clinical use of the perifollicular vascularity assessment in IVF cycles: a pilot study. Hum Reprod. 2006;21:1055–1061
  42. Baarends WM, Uilenbroek JT, Kramer P, Hoogerbrugge JW, van Leeuwen EC, Themmen AP, et al. Anti-Müllerian hormone and anti-Müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced follicle growth. Endocrinology. 1995;136:4951–4962
  43. Durlinger AL, Visser JA, Themmen AP. Regulation of ovarian function: the role of anti-Müllerian hormone. Reproduction. 2002;124:601–609
  44. Weenen C, Laven JS, Von Bergh AR, Cranfield M, Groome NP, Visser JA, et al. Anti-Müllerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod. 2004;10:77–83
  45. Ebner T, Sommergruber M, Moser M, Shebl O, Schreier-Lechner E, Tews G. Basal level of anti-Müllerian hormone is associated with oocyte quality in stimulated cycles. Hum Reprod. 2006;21(8):2022–2026
  46. Van Blerkom J, Henry G. Oocyte dysmorphism and aneuploidy in meiotically mature human oocytes after ovarian stimulation. Hum Reprod. 1992;7(3):379–390
  47. Fanchin R, Mendez Lozano DH, Frydman N, Gougeon A, Di Clemente N, Frydman R, et al. Anti-Müllerian hormone concentrations in the follicular fluid of the preovulatory follicle are predictive of the implantation potential of the ensuing embryo obtained by in vitro fertilization. J Clin Endocrinol Metab. 2007;92:1796–1802
  48. Alikani M, Palermo G, Adler A, Bertoli M, Blake M, Cohen J. Intracytoplasmic sperm injection in dysmorphic human oocytes. Zygote. 1995;3:283–288
  49. De Sutter P, Dozortsev D, Qian C, Dhont M. Oocyte morphology does not correlate with fertilization rate and embryo quality after intracytoplasmic sperm injection. Hum Reprod. 1996;11:595–597
  50. Xia P. Intracytoplasmic sperm injection: correlation of oocyte grade based on polar body, perivitelline space and cytoplasmic inclusions with fertilization rate and embryo quality. Hum Reprod. 1997;12:1750–1755
  51. Balaban B, Urman B, Sertac A, Alatas C, Aksoy S, Mercan R. Oocyte morphology does not affect fertilization rate, embryo quality and implantation rate after intracytoplasmic sperm injection. Hum Reprod. 1998;13:3431–3433
  52. Balaban B, Urman B. Effect of oocyte morphology on embryo development and implantation. Reprod Biomed Online. 2006;12:608–615
  53. Ebner T, Moser M, Tews G. Is oocyte morphology prognostic of embryo developmental potential after ICSI?. Reprod Biomed Online. 2006;2006(12):507–512
  54. Laufer N, Tarlatzis BC, DeCherney AH, Masters JT, Haseltine FP, MacLusky N. Asynchrony between human cumulus-corona cell complex and oocyte maturation after human menopausal gonadotropin treatment for in vitro fertilization. Fertil Steril. 1984;42:366–372
  55. Khamsi F, Roberge S, Lacanna IC, Wong J, Yavas Y. Effects of granulosa cells, cumulus cells, and oocyte density on in vitro fertilization in women. Endocrine. 1999;10:161–166
  56. Rattanachaiyanont M, Leader A, Leveille MC. Lack of correlation between oocyte-corona-cumulus complex morphology and nuclear maturity of oocytes collected in stimulated cycles for intracytoplasmic sperm injection. Fertil Steril. 1999;71:937–940
  57. Ebner T, Moser M, Shebl O, Sommergruber M, Yaman C, Tews G. Blood clots in the cumulus-oocyte complex predict poor oocyte quality and post-fertilization development. Reprod Biomed Online. 2008;16(6):801–807
  58. De Santis L, Cino I, Rabellotti E. Polar body morphology and spindle imaging as predictors of oocyte quality. Reprod Biomed Online. 2005;11:36–42
  59. Montag M, Schimming T, van der Ven H. Spindle imaging in human oocytes: the impact of the meiotic cell cycle. Reprod Biomed Online. 2006;12:442–446
  60. Wang WH, Meng L, Hackett RJ, Odenbourg R, Keefe DL. Limited recovery of meiotic spindles in living human oocytes after cooling-rewarming observed using polarized light microscopy. Hum Reprod. 2001;16(11):2374–2378
  61. Rienzi L, Ubaldi F, Martinez F, Iacobelli M, Minasi MG, Ferrero S, et al. Relationship between meiotic spindle location with regard to the polar body position and oocyte developmental potential after ICSI. Hum Reprod. 2003;18(6):1289–1293
  62. Eichenlaub-Ritter U, Schmiady H, Kentenich H, Soewarto D. Recurrent failure in polar body formation and premature chromosome condensation in oocytes from a human patient: indicators of asynchrony in nuclear and cytoplasmic maturation. Hum Reprod. 1995;10:2343–2349
  63. Hassan-Ali H, Hisham-Saleh A, El-Gezeiry D, Baghdady I, Ismaeil I, Mandelbaum J. Perivitelline space granularity: a sign of human menopausal gonadotrophin overdose in intracytoplasmic sperm injection. Hum Reprod. 1998;13:3425–3430
  64. Loutradis D, Drakakis P, Kallianidis K, Milingos S, Dendrinos S, Michalas S. Oocyte morphology correlates with embryo quality and pregnancy rate after intracytoplasmic sperm injection. Fertil Steril. 1999;72:240–244
  65. Ebner T, Moser M, Yaman C, Feichtinger O, Hartl J, Tews G. Elective transfer of embryos selected on the basis of first polar body morphology is associated with increased rates of implantation and pregnancy. Fertil Steril. 1999;72:599–603
  66. Ciotti PM, Notarangelo L, Morselli-Labate AM, Felletti V, Porcu E, Venturoli V. First polar body morphology before ICSI is not related to embryo quality or pregnancy rate. Hum Reprod. 2004;19:2334–2339
  67. Ebner T, Moser M, Sommergruber M, Gaiswinkler U, Shebl O, Jesacher K. Occurrence and developmental consequences of vacuoles throughout preimplantation development. Fertil Steril. 2005;83:1635–1640
  68. Serhal PF, Ranieri DM, Kinis A, Marchant S, Davies M, Khadum IM. Oocyte morphology predicts outcome of intracytoplasmic sperm injection. Hum Reprod. 1997;12:1267–1270
  69. Meriano JS, Alexis J, Visram-Zaver S, Cruz M, Casper RF. Tracking of oocyte dysmorphisms for ICSI patients may prove relevant to the outcome in subsequent patient cycles. Hum Reprod. 2001;16:2118–2123
  70. Otsuki J, Okada A, Morimoto K, Nagai Y, Kubo H. The relationship between pregnancy outcome and smooth endoplasmic reticulum clusters in MII human oocytes. Hum Reprod. 2004;19(7):1591–1597
  71. Ebner T, Moser M, Shebl O, Sommerguber M, Tews G. Prognosis of oocytes showing aggregation of smooth endoplasmic reticulum. Reprod Biomed Online. 2008;16(1):113–118
  72. Ebner T, Shebl O, Moser M, Sommergruber M, Tews G. Developmental fate of ovoid oocytes. Hum Reprod. 2008;23(1):62–66
  73. Balakier H, Bouman D, Sojecki A, Librach C, Squire JA. Morphological and cytogenetic analysis of human giant oocytes and giant embryos. Hum Reprod. 2002;17:2394–2401
  74. Rienzi L, Ubaldi FM, Iacobelli M, Minasi MG, Romano S, Ferrero S, et al. Significance of metaphase II human oocyte morphology on ICSI outcome. Fertil Steril 2008 Feb4 [Epub ahead of print].
  75. Erickson GF, Danforth DR. Ovarian control of follicle development. Am J Obstet Gynecol. 1995;172:736–747
  76. Kahraman S, Yakin K, Donmez E, Samli H, Bahce M, Cengiz G. Relationship between granular cytoplasm of oocytes and pregnancy outcome following intracytoplasmic sperm injection. Hum Reprod. 2000;15:2390–2393
  77. Mansour RT, Aboulghar MA, Serour GI, Amin YM, Ramzi AM. The effect of sperm parameters on the outcome of intracytoplasmic sperm injection. Fertil Steril. 1995;64(5):982–986
  78. Nagy ZP, Liu J, Joris H, Verheyen G, Tournaye H, Camus M, et al. The result of intracytoplasmic sperm injection is not related to any of the three basic sperm parameters. Hum Reprod. 1995;10(5):1123–1129
  79. Küpker W, Schulze W, Diedrich K. Ultrastructure of gametes and intracytoplasmic sperm injection: the significance of sperm morphology. Hum Reprod. 1998;13(Suppl. 1):99–106
  80. De Vos A, Van De Velde H, Joris H, Verheyen G, Devroey P, Van Steirteghem A. Influence of individual sperm morphology on fertilization, embryo morphology, and pregnancy outcome of intracytoplasmic sperm injection. Fertil Steril. 2003;79(1):42–48
  81. Bartoov B, Berkovitz A, Eltes F, Kogosowski A, Menezo Y, Barak Y. Real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome. J Androl. 2002;23(1):1–8
  82. Bartoov B, Berkovitz A, Eltes F, Kogosovsky A, Yagoda A, Lederman H, et al. Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection. Fertil Steril. 2003;80(6):1413–1419
  83. Berkovitz A, Eltes F, Yaari S, Katz N, Barr I, Fishman A, et al. The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm. Hum Reprod. 2005;20(1):185–190
  84. Berkovitz A, Eltes F, Lederman H, Peer S, Ellenbogen A, Feldberg B, et al. How to improve IVF-ICSI outcome by sperm selection. Reprod Biomed Online. 2006;12(5):634–638
  85. Hazout A, Dumont-Hassan M, Junca AM, Cohen Bacrie P, Tesarik J. High-magnification ICSI overcomes paternal effect resistant to conventional ICSI. Reprod Biomed Online. 2006;12(1):19–25
  86. Antinori M, Licata E, Dani G, Cerusico F, Versaci C, d'Angelo D, et al. Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial. Reprod Biomed Online. 2008;16(6):835–841
  87. Thundathil J, Palasz AT, Barth AD, Mapletoft RJ. Fertilization characteristics and in vitro embryo production with bovine sperm containing multiple nuclear vacuoles. Mol Reprod Dev. 1998;50(3):328–333
  88. Cayli S, Jakab A, Ovari L, Delpiano E, Celik-Ozenci C, Sakkas D, et al. Biochemical markers of sperm function: male fertility and sperm selection for ICSI. Reprod Biomed Online. 2003;7(4):462–468
  89. Jakab A, Sakkas D, Delpiano E, Cayli S, Kovanci E, Ward D, et al. Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies. Fertil Steril. 2005;84(6):1665–1673
  90. Huszar G, Ozenci CC, Cayli S, Zavaczki Z, Hansch E, Vigue L. Hyaluronic acid binding by human sperm indicates cellular maturity, viability, and unreacted acrosomal status. Fertil Steril. 2003;79(Suppl. 3):1616–1624
  91. Cayli S, Sakkas D, Vigue L, Demir R, Huszar G. Cellular maturity and apoptosis in human sperm: creatine kinase, caspase-3 and Bcl-XL levels in mature and diminished maturity sperm. Mol Hum Reprod. 2004;10(5):365–372
  92. Nasr-Esfahani MH, Razavi S, Vahdati AA, Fathi F, Tavalaee M. Evaluation of sperm selection procedure based on hyaluronic acid binding ability on ICSI outcome. J Assist Reprod Genet. 2008;25(5):197–203

PII: S0143-4004(08)00246-4

doi: 10.1016/j.placenta.2008.08.009

Placenta
Volume 29 , Pages 115-120 , October 2008