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Placenta
Volume 29, Issue 12
, Pages 985-994
, December 2008
Protein Nitration in Placenta – Functional Significance
References
- . Nitric oxide and peroxynitrite in health and disease. Physiol Rev. 2007;87:315–424
- . Nitric oxide, oxidants, and protein tyrosine nitration. Proc Natl Acad Sci U S A. 2004;101:4003–4008
- . Role of nitric oxide in cardiovascular disease: focus on the endothelium. Clin Chem. 1998;44:1809–1819
- . The basic chemistry of nitrogen monoxide and peroxynitrite. Free Radic Biol Med. 1998;25:385–391
- . Nitric oxide in the pathogenesis of cardiac disease. J Clin Hypertens (Greenwich). 2006;8:30–39
- . Mitochondrial nitric oxide synthase. Front Biosci. 2007;12:1072–1078
- . Constitutive calcium-dependent isoform of nitric oxide synthase in the human placental villous vascular tree. Placenta. 1993;14:373–383
- . Immunohistochemical localization of nitric oxide synthase in the human placenta. Placenta. 1993;14:487–495
- . Endothelial nitric oxide synthase in placental villous tissue from normal, pre-eclamptic and intrauterine growth restricted pregnancies. Hum Reprod. 1997;12:167–172
- . Nitric oxide concentrations are increased in the feto-placental circulation in intrauterine growth restriction. Placenta. 1996;17:165–168
- . Nitric oxide concentrations are increased in the fetoplacental circulation in preeclampsia. Am J Obstet Gynecol. 1995;173:714–718
- . Inducible (type II) nitric oxide synthase in human placental villous tissue of normotensive, pre-eclamptic and intrauterine growth-restricted pregnancies. Placenta. 1997;18:261–268
- . Oxidative stress and vascular disease. Arterioscler Thromb Vasc Biol. 2005;25:29–38
- . Oxidative stress in the placenta. Histochem Cell Biol. 2004;122:369–382
- . Expression of NADPH oxidase isoform 1 (Nox1) in human placenta: involvement in preeclampsia. Placenta. 2006;27:422–431
- . Mitochondrial nitric oxide in the signaling of cell integrated responses. Am J Physiol Cell Physiol. 2007;292:C1569–C1580
- Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol Chem Hoppe-Seyler. 1994;375:81–88
- . Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest. 1994;94:2407–2413
- . Nitrotyrosine residues in placenta. Evidence of peroxynitrite formation and action. Hypertension. 1996;28:488–493
- . Unraveling peroxynitrite formation in biological systems. Free Radic Biol Med. 2001;30:463–488
- Formation of protein tyrosine ortho-semiquinone radical and nitrotyrosine from cytochrome c-derived tyrosyl radical. J Biol Chem. 2004;
- . Nitrated cyclic GMP as a new cellular signal. Nat Chem Biol. 2007;3:687–688
- . Tyrosine nitration: localisation, quantification, consequences for protein function and signal transduction. Free Radic Res. 2001;34:541–581
- . Vascular function in the vitamin E-deprived rat: an interaction between nitric oxide and superoxide anions. Hypertension. 1998;31:830–835
- Myocardial cell death in human diabetes. Circ Res. 2000;87:1123–1132
- IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress. Diabetes. 2001;50:1414–1424
- . Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure. Cardiovasc Res. 2001;49:798–807
- . Selective nitration of prostacyclin synthase and defective vasorelaxation in atherosclerotic bovine coronary arteries. Am J Pathol. 1999;154:1359–1365
- . Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase. Am J Physiol Heart Circ Physiol. 2001;281:H2289–H2294
- Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation. Circulation. 2001;104:174–180
- Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1. Biochem Biophys Res Commun. 2004;320:639–647
- . Nitration is a mechanism of regulation of the NMDA receptor function during hypoxia. Neuroscience. 2002;112:869–877
- . Mitochondria and regulated tyrosine nitration. Biochem Soc Trans. 2005;33:1399–1403
- . Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys. 1998;356:1–11
- Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA. 2003;289:1675–1680
- . Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. Proc Natl Acad Sci U S A. 1996;93:15069–15074
- . DNA strand breakage, activation of poly(ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci U S A. 1996;93:1753–1758
- Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2000;278:L961–L967
- Nitric oxide (NO) induces nitration of protein kinase cepsilon (PKCepsilon), facilitating PKCepsilon translocation via enhanced PKCepsilon–RACK2 interactions. A novel mechanism of NO-triggered activation of PKC epsilon. J Biol Chem. 2002;277:15021–15027
- . Biochemistry of protein tyrosine nitration in cardiovascular pathology. Cardiovasc Res. 2007;75:291–302
- . Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences. Arch Biochem Biophys. 2001;394:167–172
- . Nitric oxide nitrates tyrosine residues of tumor-suppressor p53 protein in MCF-7 cells. Biochem Biophys Res Commun. 2000;267:609–613
- . Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (Y34F) by peroxynitrite. Arch Biochem Biophys. 1999;366:82–88
- . Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro. Free Radic Biol Med. 2001;30:986–991
- . Regulation of xanthine oxidase by nitric oxide and peroxynitrite. J Biol Chem. 2000;275:9369–9376
- . Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues. Biochemistry. 1998;37:1613–1622
- Proteolytic degradation of tyrosine nitrated proteins. Arch Biochem Biophys. 2000;380:360–366
- . Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. J Biol Chem. 1998;273:10857–10862
- . Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett. 1996;385:63–66
- . Degradation of oxidized proteins in mammalian cells. FASEB J. 1997;11:526–534
- . Comparative resistance of the 20S and 26S proteasome to oxidative stress. Biochem J. 1998;335:637–642
- Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress. J Biol Chem. 1997;272:28218–28226
- . Activation of the cell death program by nitric oxide involves inhibition of the proteasome. J Biol Chem. 1999;274:19581–19586
- Proteomic method identifies proteins nitrated in vivo during inflammatory challenge. Proc Natl Acad Sci U S A. 2001;98:12056–12061
- . p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite. Neurosci Res. 1999;33:325–328
- . Angiotensin II induces tyrosine nitration and activation of ERK1/2 in vascular smooth muscle cells. FEBS Lett. 2005;579:5100–5104
- . Mitogen-activated protein kinase phosphorylation in kidneys of beta(s) sickle cell mice. J Am Soc Nephrol. 2000;11:1026–1032
- . Nitration of p38 MAPK in the placenta: association of nitration with reduced catalytic activity of p38 MAPK in pre-eclampsia. Mol Hum Reprod. 2006;
- . Peroxynitrite treatment in vitro disables catalytic activity of recombinant p38 MAPK. Proteomics. 2006;6:4838–4844
- . Peroxynitrite modulates tyrosine-dependent signal transduction pathway of human erythrocyte band 3. FASEB J. 1997;11:1281–1290
- . Rapid and irreversible inactivation of protein tyrosine phosphatases PTP1B, CD45, and LAR by peroxynitrite. Arch Biochem Biophys. 1999;369:197–207
- . Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts. Biochem J. 2000;352(Pt 1):219–225
- . Peroxynitrite induces covalent dimerization of epidermal growth factor receptors in A431 epidermoid carcinoma cells. J Biol Chem. 1998;273:31860–31866
- . Peroxynitrite inhibits epidermal growth factor receptor signaling in Caco-2 cells. Dig Dis Sci. 2003;48:2353–2359
- . Cellular functions regulated by src family kinases. Annu Rev Cell Dev Biol. 1997;13:513–609
- . Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun. 2005;331:1–14
- . Src-family kinases: rheostats of immune cell signaling. Mol Immunol. 2004;41:631–643
- Evidence of a novel redox-linked activation mechanism for the Src kinase which is independent of tyrosine 527-mediated regulation. Oncogene. 1996;13:2615–2622
- . Peroxynitrite-dependent activation of src tyrosine kinases lyn and hck in erythrocytes is under mechanistically different pathways of redox control. Free Radic Biol Med. 2001;30:1108–1117
- . Nitrotyrosine mimics phosphotyrosine binding to the SH2 domain of the src family tyrosine kinase lyn. FEBS Lett. 2001;503:189–195
- . Denitration of peroxynitrite-treated proteins by ‘protein nitratases’ from rat brain and heart. Mol Cell Biochem. 1999;201:11–16
- . Protein denitration/modification by Escherichia coli nitrate reductase and mammalian cytochrome P-450 reductase. Front Biosci. 2002;7:9–14
- . The role of protein nitration in the inhibition of platelet activation by peroxynitrite. FEBS Lett. 2002;511:59–64
- . Rapid and selective oxygen-regulated protein tyrosine denitration and nitration in mitochondria. J Biol Chem. 2004;279:27257–27262
- . Antibodies against nitric oxide damaged poly-l-tyrosine and 3-nitrotyrosine levels in systemic lupus erythematosus. J Biochem Mol Biol. 2006;39:189–196
- . Prevalence of anti-3-nitrotyrosine antibodies in the joint synovial fluid of patients with rheumatoid arthritis, osteoarthritis and systemic lupus erythematosus. Clin Chim Acta. 2006;370:100–107
- Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis. Arthritis Rheum. 2006;54:343–355
- . Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology. Free Radic Biol Med. 2002;32:841–859
- . NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response?. Trends Biochem Sci. 2003;28:646–654
- . Factors determining the selectivity of protein tyrosine nitration. Arch Biochem Biophys. 1999;371:169–178
- . Repair of peroxynitrite damage to tubulin by the thioredoxin reductase system. Free Radic Biol Med. 2004;36:497–506
- Peroxynitrite mediates TNF-alpha-induced endothelial barrier dysfunction and nitration of actin. Am J Physiol Lung Cell Mol Physiol. 2006;290:L674–L684
- Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies. J Neurosci. 2006;26:10636–10645
- . Effect of nitration on the activity of bovine erythrocyte Cu, Zn-superoxide dismutase (BESOD) and a kinetic analysis of its dimerization-dissociation reaction as examined by subunit exchange between the native and nitrated BESODs. J Biochem. 2003;134:683–690
- Protein tyrosine nitration in hydrophilic and hydrophobic environments. Amino Acids. 2007;32:501–515
- . Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration. J Biol Chem. 2001;276:11631–11638
- Cytochrome c nitration by peroxynitrite. J Biol Chem. 2000;275:21409–21415
- . Peroxynitrite and protein tyrosine nitration of prostacyclin synthase. Prostaglandins Other Lipid Mediat. 2007;82:119–127
- . Peroxynitrite reaction with heme proteins. Nitric Oxide. 1999;3:142–152
- Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe N-t-BOC-l-tyrosine tert-butyl ester. Biochemistry. 2006;45:6813–6825
- . Aspects, mechanism, and biological relevance of mitochondrial protein nitration sustained by mitochondrial nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2004;286:H22–H29
- . Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertension. 1998;31:1065–1069
- . Pre-eclampsia: contribution of maternal constitutional factors and the consequences for cardiovascular health. Clin Exp Pharmacol Physiol. 2006;33:826–830
- . Pregnancy: a stress test for life. Curr Opin Obstet Gynecol. 2003;15:465–471
- . Preeclampsia and future cardiovascular risk. Expert Rev Cardiovasc Ther. 2007;5:283–294
- . Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia. Am J Physiol Heart Circ Physiol. 2000;278:H1311–H1319
- . Evidence for peroxynitrite formation in the vasculature of women with preeclampsia. Hypertension. 1999;33:83–89
- . Metabolic syndrome and higher risk of maternal placental syndromes and cardiovascular disease. Drug Dev Res. 2006;67:607–611
- Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. Mol Cell. 2000;6:109–116
- . Nuclear factor-{kappa}B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant vitamins. Am J Pathol. 2007;170:1511–1520
- . Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins. Am J Physiol Lung Cell Mol Physiol. 2007;293:L1012–L1020
- . Post-translational modifications of the P2X(4) purinergic receptor subtype in the human placenta are altered in preeclampsia. Placenta. 2007;28:270–277
- Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity. Biochem J. 2002;366:399–404
- . Pregnancy, vascular tone, and maternal hemodynamics: a crucial adaptation. Obstet Gynecol Surv. 2000;55:574–581
- . Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. Pharmacol Rev. 1978;30:293–331
- . Diffusion of peroxynitrite into the human platelet inhibits cyclooxygenase via nitration of tyrosine residues. J Pharmacol Exp Ther. 2000;293:222–229
- . Tyrosine nitration as a mechanism of selective inactivation of prostacyclin synthase by peroxynitrite. Biol Chem. 1997;378:707–713
- . Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia. Am J Obstet Gynecol. 1992;167:946–949
- . Regulation of cyclooxygenase enzymes by nitric oxide. Cell Mol Life Sci. 1997;53:576–582
- Nitric oxide synthase/COX cross-talk: nitric oxide activates COX-1 but inhibits COX-2-derived prostaglandin production. J Immunol. 2000;165:1582–1587
- Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia. Prostaglandins. 1980;20:105–110
- . Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation. FASEB J. 2003;17:914–916
- . Prostacyclin in the cardiovascular system: new aspects and open questions. Pharmacol Rep. 2005;57(Suppl.):120–126
- . Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol. 1999;180:499–506
- . The sources of oxidative stress in the vessel wall. Kidney Int. 2005;67:1659–1661
- . Superoxide: a key player in hypertension. FASEB J. 2004;18:94–101
- . How do blood vessels age? Mechanisms and clinical implications. Vasa. 2004;33:3–11
- . Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res. 1998;82:1298–1305
- . Placental mitochondria as a source of oxidative stress in pre-eclampsia. Placenta. 1998;19:581–586
- . Mitochondria and apoptosis. Science. 1998;281:1309–1312
- . Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat Neurosci. 1998;1:366–373
- Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J Neurosci. 1998;18:687–697
- . Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells. J Neurosci Res. 1998;51:293–308
- . Peroxynitrite reactions and formation in mitochondria. Free Radic Biol Med. 2002;33:1451–1464
- . Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc Natl Acad Sci U S A. 1996;93:11853–11858
- . Invited review: manganese superoxide dismutase in disease. Free Radic Res. 2001;34:325–336
- . Nitration of manganese superoxide dismutase during ocular inflammation. Exp Eye Res. 2002;74:463–471
- Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med. 2000;192:1731–1744
- SOD2 knockdown mouse model of early AMD. Invest Ophthalmol Vis Sci. 2007;48:4407–4420
- . Survival, lung injury, and lung protein nitration in heterozygous MnSOD knockout mice in hyperoxia. Exp Lung Res. 1999;25:631–646
- . Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol. 2002;186:158–166
- Nitric oxide inhibits mitochondrial NADH: ubiquinone reductase activity through peroxynitrite formation. Biochem J. 2001;359:139–145
- . Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry. J Biol Chem. 2003;278:37223–37230
- . Nitric oxide and calcium together inactivate mitochondrial complex I and induce cytochrome c release. J Mol Cell Cardiol. 2003;35:803–809
- . Metabolic syndrome and the risk of placental dysfunction. J Obstet Gynaecol Can. 2005;27:1095–1101
- . Endocrine regulation of human fetal growth: the role of the mother, placenta, and fetus. Endocr Rev. 2006;27:141–169
- . Aberrations in placental cytokine mRNA related to intrauterine growth retardation. Pediatr Res. 2002;51:201–206
- . High altitude residence during pregnancy alters cytokine and catecholamine levels. Am J Reprod Immunol. 2002;48:344–354
- . Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation. 2005;111:1448–1454
- Obesity is the major determinant of elevated C-reactive protein in subjects with the metabolic syndrome. Int J Obes Relat Metab Disord. 2004;28:674–679
- Adiponectin in human pregnancy: implications for regulation of glucose and lipid metabolism. Diabetologia. 2006;49:1677–1685
- . The human placenta in gestational diabetes mellitus: the insulin and cytokine network. Diabetes Care. 2007;30:S120–S126
- . Gestational diabetes induces placental genes for chronic stress and inflammatory pathways. Diabetes. 2003;52:2951–2958
- Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. J Immunol. 2003;171:3245–3252
- Chronic hypoxia in vivo reduces placental oxidative stress. Placenta. 2007;28:846–853
- Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease. Gut. 2003;52:720–728
- . Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic Res. 2000;33(Suppl.):S99–S108
- . Plasma protein carbonyl and thiol stress before and after laparoscopic gastric banding in morbidly obese patients. Obes Surg. 2007;17:1367–1373
- . Protein carbonyls in decidua and placenta of pre-eclamptic women as markers for oxidative stress. Placenta. 2001;22:213–219
- . Protein carbonyl groups as biomarkers of oxidative stress. Clin Chim Acta. 2003;329:23–38
- . Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death Differ. 2004;11(Suppl. 1):S56–S64
- . Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler Thromb Vasc Biol. 2005;25:2623–2629
- . Effects of peroxynitrite on sarco/endoplasmic reticulum Ca2+ pump isoforms SERCA2b and SERCA3a. Am J Physiol Cell Physiol. 2003;285:C1537–C1543
- . Emergence of endoplasmic reticulum stress and activated microglia in Purkinje cell degeneration mice. Neurosci Lett. 2006;396:91–96
- . Involvement of endoplasmic reticulum stress on the cell death induced by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells. Neurochem Res. 2006;31:657–664
- . Endoplasmic reticulum stress exacerbates ischemia-reperfusion-induced apoptosis through attenuation of Akt protein synthesis in human choriocarcinoma cells. FASEB J. 2007;21:872–884
- . Differences in the proteome profile in placenta from normal term and preeclamptic preterm pregnancies. Proteomics Clin Appl. 2007;1:446–456
- . A review of approaches to the analysis of 3-nitrotyrosine. Amino Acids. 2003;25:351–361
- Association between nitrotyrosine levels and microvascular density in human breast cancer. Breast Cancer Res Treat. 2002;74:271–278
- Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation. J Immunol. 2006;176:5587–5597
- . Inflammatory and oxidative markers in atherosclerosis: relationship to outcome. Curr Atheroscler Rep. 2004;6:243–250
- . In vivo disposition of 3-nitro-L-tyrosine in rats: implications on tracking systemic peroxynitrite exposure. Drug Metab Dispos. 1999;27:429–431
- Urinary excretion of the nitrotyrosine metabolite 3-nitro-4 hydroxyphenylacetic acid in preterm and term infants. Neonatology. 2007;93:73–76
- . Genetically encoding protein oxidative damage. J Am Chem Soc. 2008;130:4028–4033
PII: S0143-4004(08)00305-6
doi: 10.1016/j.placenta.2008.09.003
© 2008 Elsevier Ltd. All rights reserved.
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Placenta
Volume 29, Issue 12
, Pages 985-994
, December 2008
