Hyperosmolar Stress Induces Global mRNA Responses in Placental Trophoblast Stem Cells that Emulate Early Post-implantation Differentiation

Liu, J.; Xu, W.; Sun, T.; Wang, F.; Puscheck, E.; Brigstock, D.; Wang, Q.T.; Davis, R.; Rappolee, D.A.

doi:10.1016/j.placenta.2008.10.009

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Volume 30, Issue 1 , Pages 66-73, January 2009

Hyperosmolar Stress Induces Global mRNA Responses in Placental Trophoblast Stem Cells that Emulate Early Post-implantation Differentiation

J. Liu
- C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
W. Xu
- Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, MI 48201, USA
T. Sun
- C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
F. Wang
- C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
E. Puscheck
- C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
D. Brigstock
- Department of Surgery, Ohio State University and Children's Hospital, Columbus, OH 43205, USA
- Department of Medical Biochemistry, Ohio State University and Children's Hospital, Columbus, OH 43205, USA
Q.T. Wang
- Department of Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA
- Department of Biochemistry and Department of Developmental Biology and Genetics, Stanford University, CA 94305, USA
R. Davis
- Department of Biochemistry and Department of Developmental Biology and Genetics, Stanford University, CA 94305, USA
D.A. Rappolee
- C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
- Department of Reproductive Sciences and Physiology, Wayne State University School of Medicine, MI 48201, USA
- Karmanos Cancer Institute, Wayne State University School of Medicine, MI 48201, USA
- Institutes for Environmental Health Science, Wayne State University School of Medicine, MI 48201, USA
- Department of Biology, University of Windsor, Windsor, Ontario, Canada N9B 3P4
- Correspondence to: D.A. Rappolee, C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI 48201, USA. Tel.: +1 313 577 1228; fax: +1 313 577 8554.