« Previous
Next »
Placenta
Volume 30
, Pages 49-54
, March 2009
Factors Involved in Regulating Trophoblast Fusion: Potential Role in the Development of Preeclampsia
References
- . Pre-eclampsia. Lancet. 2000;356(9237):1260–1265
- . Pathogenesis and genetics of pre-eclampsia. Lancet. 2001;357(9249):53–56
- . Latest advances in understanding preeclampsia. Science. 2005;308(5728):1592–1594
- First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction. Am J Obstet Gynecol. 2007;197(1):35;e1–7
- . Longitudinal determination of serum placental protein 13 during development of preeclampsia. Fetal Diagn Ther. 2008;24(3):230–236
- . Placental origins of preeclampsia: challenging the current hypothesis. Hypertension. 2008;51(4):970–975
- . Fusion of cytotrophoblast with syncytiotrophoblast in the human placenta: factors involved in syncytialization. J Reprod Med Endocrinol. 2008;5(2):76–82
- . Studies of placental morphogenesis. I. Radioautographic studies of human placenta utilizing tritiated thymidine. Proc Soc Exp Biol Med. 1961;106:829–831
- . Apoptosis cascade progresses during turnover of human trophoblast: analysis of villous cytotrophoblast and syncytial fragments in vitro. Lab Invest. 1999;79(12):1687–1702
- . Transcriptional activity in the syncytiotrophoblast of the human placenta. Placenta. 2008;29(8):A95
- . Stalk model of membrane fusion: solution of energy crisis. Biophys J. 2002;82(2):882–895
- . Membrane fusion: stalk model revisited. Biophys J. 2002;82(2):693–712
- . Observation of a membrane fusion intermediate structure. Science. 2002;297(5588):1877–1879
- . Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion. Curr Opin Cell Biol. 1995;7(4):509–517
- . The fusion pore and mechanisms of biological membrane fusion. Curr Opin Cell Biol. 1996;8(4):524–533
- . Epidermal growth factor induces differentiation and secretion of human chorionic gonadotropin and placental lactogen in normal human placenta. J Clin Endocrinol Metab. 1987;65(6):1282–1290
- . Vascular endothelial growth factor but not placental growth factor promotes trophoblast syncytialization in vitro. J Soc Gynecol Investig. 2001;8(6):341–346
- . Demonstration of functional cytokine-placental interactions: CSF-1 and GM-CSF stimulate human cytotrophoblast differentiation and peptide hormone secretion. Exp Cell Res. 1994;214(1):46–54
- . The central role of human chorionic gonadotropin in the formation of human placental syncytium. Endocrinology. 2003;144(3):1108–1120
- . Novel role of human chorionic gonadotropin in differentiation of human cytotrophoblasts. Endocrinology. 1993;132(3):1387–1395
- . Tumour necrosis factor-alpha impairs chorionic gonadotrophin beta-subunit expression and cell fusion of human villous cytotrophoblast. Mol Hum Reprod. 2006;12(10):601–609
- . Transforming growth factor beta 1 inhibits placental differentiation and human chorionic gonadotropin and human placental lactogen secretion. Endocrinology. 1991;129(1):22–26
- Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med. 2006;12(6):642–649
- . Soluble endoglin is an accurate predictor and a pathogenic molecule in pre-eclampsia. Nephrol Dial Transplant. 2007;22(3):712–714
- . PL74, a novel member of the transforming growth factor-beta superfamily, is overexpressed in preeclampsia and causes apoptosis in trophoblast cells. J Clin Endocrinol Metab. 2005;90(5):3045–3053
- . ERK1/2 and p38 regulate trophoblasts differentiation in human term placenta. J Physiol. 2005;566(Pt 2):409–423
- Stimulation of GCMa and syncytin via cAMP mediated PKA signaling in human trophoblastic cells under normoxic and hypoxic conditions. FEBS Lett. 2005;579(18):3991–3998
- . Biochemical characterization of the human placental transcription factor GCMa/1. Biochem Cell Biol. 2005;83(2):188–195
- . Complex patterns of GCM1 mRNA and protein in villous and extravillous trophoblast cells of the human placenta. Placenta. 2004;25(6):553–559
- . A GCM motif protein is involved in placenta-specific expression of human aromatase gene. J Biol Chem. 1999;274(45):32279–32286
- GCMa regulates the syncytin-mediated trophoblastic fusion. J Biol Chem. 2002;277(51):50062–50068
- Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature. 2000;403(6771):785–789
- Direct involvement of HERV-W Env glycoprotein in human trophoblast cell fusion and differentiation. Mol Cell Biol. 2003;23(10):3566–3574
- . CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues. Exp Cell Res. 2006;312(7):1011–1020
- . Amino acid transporters in the human placenta. Pediatr Res. 2001;49(2):141–147
- . Human placental amino acid transporter genes: expression and function. Reproduction. 2002;124(5):593–600
- . Manipulation of CD98 expression affects both trophoblast cell fusion and amino acid transport activity during syncytialization of human placental BeWo cells. J Physiol. 2003;550(Pt 1):3–9
- . RNA interference-induced reduction in CD98 expression suppresses cell fusion during syncytialization of human placental BeWo cells. FEBS Lett. 2004;577(3):473–477
- . Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells–implication for placental cell fusion. FEBS J. 2007;274(11):2715–2727
- Functional analyses of placental protein 13/galectin-13. Eur J Biochem. 2004;271(6):1065–1078
- . Longitudinal determination of serum placental protein 13 during development of preeclampsia. Fetal Diagn Ther. 2008;24:230–236
- Involvement of connexin 43 in human trophoblast cell fusion and differentiation. J Cell Sci. 2003;116(Pt 16):3413–3421
- . Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ. 2003;10(1):76–100
- Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J Invest Dermatol. 2000;115(6):1148–1151
- . A role for caspases in lens fiber differentiation. J Cell Biol. 1998;140(1):153–158
- . Caspase activation in the terminal differentiation of human epidermal keratinocytes. Curr Biol. 1999;9(7):361–364
- . Syncytial fusion of human trophoblast depends on caspase 8. Cell Death Differ. 2004;11(1):90–98
- . Caspase-14: a new player in cytotrophoblast differentiation. Reprod Biomed Online. 2007;14(3):300–307
- . ADAMs and cell fusion. Curr Opin Cell Biol. 1996;8(5):692–699
- . Structure-function analysis of the ADAM family of disintegrin-like and metalloproteinase-containing proteins (review). J Protein Chem. 1999;18(4):447–465
- . Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion. J Biol Chem. 2000;275(18):13933–13939
- . Meltrin-alpha, a fusion protein involved in multinucleated giant cell and osteoclast formation. Calcif Tissue Int. 1999;64(6):508–515
- . A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo. J Biol Chem. 1998;273(1):157–166
- . Amniotic fluid and plasma concentrations of pregnancy-associated plasma protein-A (PAPP-A) throughout pregnancy: comparison with other fetoplacental products. Br J Obstet Gynaecol. 1982;89(5):358–363
- Expression of pregnancy-associated plasma protein-A (PAPP-A) during human villous trophoblast differentiation in vitro. Placenta. 2003;24(5):532–539
- . Modulation of PAPP-A expression by PPARgamma in human first trimester trophoblast. Placenta. 2006;27(Suppl. A):S127–S134
- Hypoxia impairs cell fusion and differentiation process in human cytotrophoblast, in vitro. J Cell Physiol. 1996;168(2):346–353
- . Proteomic analysis of hypoxia-induced responses in the syncytialization of human placental cell line BeWo. Placenta. 2007;28(5–6):399–407
- . Hypoxia alters expression and function of syncytin and its receptor during trophoblast cell fusion of human placental BeWo cells: implications for impaired trophoblast syncytialisation in pre-eclampsia. Biochim Biophys Acta. 2003;1638(1):63–71
- . General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA. 1993;90(9):4304–4308
- . Hypoxia prevents induction of aromatase expression in human trophoblast cells in culture: potential inhibitory role of the hypoxia-inducible transcription factor Mash-2 (mammalian achaete-scute homologous protein-2). Mol Endocrinol. 2000;14(10):1661–1673
- Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am J Physiol Regul Integr Comp Physiol. 2006;291(4):R1085–R1093
- . Onset of maternal arterial blood flow and placental oxidative stress. A possible factor in human early pregnancy failure. Am J Pathol. 2000;157(6):2111–2122
- . Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd collection revisited. Am J Obstet Gynecol. 1999;181(3):718–724
- . Placental expression of the transcription factor NRF2 is altered in preeclampsia. Placenta. 2008;29(8):A58
- . Molecular mechanism of nrf2 activation by oxidative stress. Antioxid Redox Signal. 2005;7(11–12):1664–1673
- . A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies. Br J Obstet Gynaecol. 1994;101(8):669–674
- Placental bed spiral arteries in the hypertensive disorders of pregnancy. Br J Obstet Gynaecol. 1991;98(7):648–655
- . Trophoblast alterations in the placental bed in relation to physiological changes in spiral arteries. Br J Obstet Gynaecol. 1983;90(1):34–39
- . Elevation of granulocyte-macrophage colony-stimulating factor in the placenta and blood in preeclampsia. Am J Obstet Gynecol. 2004;190(2):456–461
- . Placental stem cell markers in pre-eclampsia. Int J Gynaecol Obstet. 2008;100(3):228–233
- . Soluble endoglin (sEng) joins the soluble fms-like tyrosine kinase (sFlt) receptor as a pre-eclampsia molecule. Nephrol Dial Transplant. 2006;21(11):3052–3054
- . Correlation between soluble endoglin, vascular endothelial growth factor receptor-1, and adipocytokines in preeclampsia. J Clin Endocrinol Metab. 2007;92(7):2672–2679
- . Decreased placental GCM1 (glial cells missing) gene expression in pre-eclampsia. Placenta. 2004;25(5):413–421
- Impaired cytotrophoblast cell-cell fusion is associated with reduced Syncytin and increased apoptosis in patients with placental dysfunction. Mol Reprod Dev. 2008;75(1):175–183
- . Altered placental syncytin and its receptor ASCT2 expression in placental development and pre-eclampsia. BJOG. 2006;113(2):152–158
- . The placenta in pre-eclampsia and intrauterine growth restriction: studies on exchange surface areas, diffusion distances and villous membrane diffusive conductances. Placenta. 2007;28(2–3):233–238
- . Proliferation of villous trophoblast of the human placenta in normal and abnormal pregnancies. Virchows Arch B Cell Pathol Incl Mol Pathol. 1991;60(6):365–372
- . Caspases rather than calpains regulate fusion of BeWo cells and primary trophoblast as visualized by fodrin cleavage. Placenta. 2008;29(8):A5
- . Trophoblast fusion: fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion. Micron. 2006;37(6):509–517
- . Intercellular fusion of BeWo. Placenta. 2005;26(8–9):686;author reply 687
- . Monoclonal antiphosphatidylserine antibody inhibits intercellular fusion of the choriocarcinoma line, JAR. Biol Reprod. 1995;53(4):905–910
- . Modulation of phosphatidylserine epitope expression by BeWo cells during forskolin treatment. Placenta. 1993;14(2):177–186
PII: S0143-4004(08)00353-6
doi: 10.1016/j.placenta.2008.10.011
© 2009 IFPA and Elsevier Ltd. All rights reserved.
« Previous
Next »
Placenta
Volume 30
, Pages 49-54
, March 2009
