Placenta
Volume 30, Issue 2 , Pages 149-155 , February 2009

Characterization of the Placental Macrophage Secretome: Implications for Antiviral Activity

  • K. García

      Affiliations

    • Department of Microbiology and Medical Zoology, San Juan 00935, Puerto Rico
    • ,
  • V. García

      Affiliations

    • Department of Microbiology and Medical Zoology, San Juan 00935, Puerto Rico
    • ,
  • J. Pérez Laspiur

      Affiliations

    • RCMI Clinical Proteomics Core, University of Puerto Rico Medical Sciences Campus, Puerto Rico
    • ,
  • F. Duan

      Affiliations

    • Biostatistics, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA
    • ,
  • L.M. Meléndez

      Affiliations

    • Department of Microbiology and Medical Zoology, San Juan 00935, Puerto Rico
    • RCMI Clinical Proteomics Core, University of Puerto Rico Medical Sciences Campus, Puerto Rico
    • Corresponding Author InformationCorresponding author. Department of Microbiology and Medical Zoology, Biomedical Building I, 3rd Floor Suite 310, San Juan 00935, Puerto Rico. Tel.: +787 777 0079; fax: +787 777 0078.

,Accepted 27 October 2008.

References 

  1. Nahmias A, Abramowsky C, Dobronyi I, Ibegbu C, Henderson S. Infection and immunity at the maternal–placental–fetal interface: focus on HIV-1. Trophoblast Res. 1998;12:103–124
  2. Anderson VM. The placental barrier to maternal HIV infection. Obstet Gynecol Clin North Am. 1997;24:797–820
  3. Mofenson LM. Mother–child HIV-1 transmission: timing and determinants. Obstet Gynecol Clin North Am. 1997;24:759–784
  4. Gustafsson C, Mjosberg J, Matussek A, Geffers R, Matthiesen L, Berg G, et al. Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype. PLoS ONE. 2008;3:e2078
  5. Szekeres-Bartho J. Regulation of NK cell cytotoxicity during pregnancy. Reprod Biomed Online. 2008;16:211–217
  6. Kammerer U, Eggert AO, Kapp M, McLellan AD, Geijtenbeek TB, Dietl J, et al. Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy. Am J Pathol. 2003;162:887–896
  7. Patterson BK, Tjernlund A, Andersson J. Endogenous inhibitors of HIV: potent anti-HIV activity of leukemia inhibitory factor. Curr Mol Med. 2002;2:713–722
  8. Kondapi AK, Hafiz MA, Sivaram T. Anti-HIV activity of a glycoprotein from first trimester placental tissue. Antiviral Res. 2002;54:47–57
  9. Chakraborty PD, Bhattacharyya D. In vitro growth inhibition of microbes by human placental extract. Curr Sci. 2005;88:782–786
  10. Kim HS, Cho JH, Park HW, Yoon H, Kim MS, Kim SC. Endotoxin-neutralizing antimicrobial proteins of the human placenta. J Immunol. 2002;168:2356–2364
  11. Nahmias AJ, Kourtis AP. The great balancing acts. The pregnant woman, placenta, fetus, and infectious agents. Clin Perinatol. 1997;24:497–521
  12. Kesson AM, Fear WR, Kazazi F, Mathijs JM, Chang J, King NJ, et al. Human immunodeficiency virus type 1 infection of human placental macrophages in vitro. J Infect Dis. 1993;168:571–579
  13. Kesson AM, Fear WR, Williams L, Chang J, King NJ, Cunningham AL. HIV infection of placental macrophages: their potential role in vertical transmission. J Leukoc Biol. 1994;56:241–246
  14. McGann KA, Collman R, Kolson DL, Gonzalez-Scarano F, Coukos G, Coutifaris C, et al. Human immunodeficiency virus type 1 causes productive infection of macrophages in primary placental cell cultures. J Infect Dis. 1994;169:746–753
  15. Fear WR, Kesson AM, Naif H, Lynch GW, Cunningham AL. Differential tropism and chemokine receptor expression of human immunodeficiency virus type 1 in neonatal monocytes, monocyte-derived macrophages, and placental macrophages. J Virol. 1998;72:1334–1344
  16. Melendez-Guerrero LM, Holmes R, Backé E, Polliotti B, Ibegbu C, Lee F, et al. In vitro infection of Hofbauer cells with a monocyte-tropic strain of HIV-1. Trophoblast Res. 1994;8:33–45
  17. Plaud-Valentin M, Delgado R, Garcia V, Zorrilla C, Gandia J, Melendez-Guerrero LM. HIV infection of placental macrophages: effect on the secretion of HIV stimulatory cytokines. Cell Mol Biol (Noisy-le-grand). 1999;45:423–431
  18. Torres G, Garcia V, Sanchez E, Segarra A, Patterson BK, Melendez-Guerrero LM. Expression of the HIV-1 co-receptors CCR5 and CXCR4 on placental macrophages and the effect of IL-10 on their expression. Placenta. 2001;22(Suppl. A):S29–S33
  19. Melendez J, Garcia V, Sanchez E, Delgado R, Torres G, Melendez-Guerrero LM. Is decreased HIV-1 infectivity of placental macrophages caused by high levels of beta-chemokines?. Cell Mol Biol (Noisy-le-grand). 2001;47:OL51–OL59[Online Pub]
  20. Uren S, Boyle W. Isolation of macrophages from human placenta. J Immunol Methods. 1985;78:25–34
  21. Ciborowski P, Kadiu I, Rozek W, Smith L, Bernhardt K, Fladseth M, et al. Investigating the human immunodeficiency virus type 1-infected monocyte-derived macrophage secretome. Virology. 2007;363:198–209
  22. Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M. Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics. 2002;18(Suppl. 1):S96–S104
  23. Beyer S, Walter Y, Hellmann J, Kramer PJ, Kopp-Schneider A, Kroeger M, et al. Comparison of software tools to improve the detection of carcinogen induced changes in the rat liver proteome by analyzing SELDI-TOF-MS spectra. J Proteome Res. 2006;5:254–261
  24. Luciano-Montalvo C, Ciborowski P, Duan F, Gendelman H, Meléndez L. Proteomic analyses associate cystatin B with restricted HIV-1 replication in placental macrophages. Placenta. 2008;29:1016–1023[Epub 2008 Oct 31]
  25. Luo X, Carlson KA, Wojna V, Mayo R, Biskup TM, Stoner J, et al. Macrophage proteomic fingerprinting predicts HIV-1-associated cognitive impairment. Neurology. 2003;60:1931–1937
  26. Wojna V, Carlson KA, Luo X, Mayo R, Melendez LM, Kraiselburd E, et al. Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study. J Neurovirol. 2004;10(Suppl. 1):74–81
  27. Seo MS, Kang SW, Kim K, Baines IC, Lee TH, Rhee SG. Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate. J Biol Chem. 2000;275:20346–20354
  28. Krutilina RI, Kropotov AV, Leutenegger C, Serikov VB. Migrating leukocytes are the source of peroxiredoxin V during inflammation in the airways. J Inflamm (Lond). 2006;3:13
  29. Geiben-Lynn R, Kursar M, Brown NV, Addo MM, Shau H, Lieberman J, et al. HIV-1 antiviral activity of recombinant natural killer cell enhancing factors, NKEF-A and NKEF-B, members of the peroxiredoxin family. J Biol Chem. 2003;278:1569–1574
  30. Jin DY, Chae HZ, Rhee SG, Jeang KT. Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation. J Biol Chem. 1997;272:30952–30961
  31. Chertova E, Chertov O, Coren LV, Roser JD, Trubey CM, Bess JW, et al. Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages. J Virol. 2006;80:9039–9052
  32. Misse D, Yssel H, Trabattoni D, Oblet C, Lo Caputo S, Mazzotta F, et al. IL-22 participates in an innate anti-HIV-1 host-resistance network through acute-phase protein induction. J Immunol. 2007;178:407–415
  33. Kang SW, Rhee SG, Chang TS, Jeong W, Choi MH. 2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications. Trends Mol Med. 2005;11:571–578
  34. Verdot L, Lalmanach G, Vercruysse V, Hartmann S, Lucius R, Hoebeke J, et al. Cystatins up-regulate nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages. J Biol Chem. 1996;271:28077–28081
  35. Verdot L, Lalmanach G, Vercruysse V, Hoebeke J, Gauthier F, Vray B. Chicken cystatin stimulates nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages via cytokine synthesis. Eur J Biochem. 1999;266:1111–1117
  36. Blond D, Raoul H, Le Grand R, Dormont D. Nitric oxide synthesis enhances human immunodeficiency virus replication in primary human macrophages. J Virol. 2000;74:8904–8912
  37. Jimenez JL, Gonzalez-Nicolas J, Alvarez S, Fresno M, Munoz-Fernandez MA. Regulation of human immunodeficiency virus type 1 replication in human T lymphocytes by nitric oxide. J Virol. 2001;75:4655–4663
  38. Schutyser E, Richmond A, Van Damme J. Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. J Leukoc Biol. 2005;78:14–26
  39. Schraufstatter I, Takamori H, Sikora L, Sriramarao P, DiScipio RG. Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages. Am J Physiol Lung Cell Mol Physiol. 2004;286:L494–L501

PII: S0143-4004(08)00365-2

doi: 10.1016/j.placenta.2008.10.014

Placenta
Volume 30, Issue 2 , Pages 149-155 , February 2009

Article Tools

* Image Usage & Resolution