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Placenta
Volume 30, Issue 3
, Pages 263-269
, March 2009
Influx Mechanism of 2′,3′-Dideoxyinosine and Uridine at the Blood–Placenta Barrier
References
- . Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection. J Clin Pharm Ther. 2007;32(3):293–311
- . Maternal transmission of retroviral disease: transgenic mice as a rapid test system for evaluating perinatal and transplacental antiretroviral therapy. Proc Natl Acad Sci USA. 1988;85(24):9792–9796
- . Transfer and metabolism of dideoxyinosine by the perfused human placenta. J Acquir Immune Defic Syndr. 1993;6(1):2–6
- . Schenken RS, Schenker S. Transfer of dideoxyinosine across the human isolated placenta. Br J Clin Pharmacol. 1994;38(3):237–242
- . Development of passive permeability characteristics of rat placenta during the last third of gestation. Am J Physiol. 1991;261(6 Pt 2):R1461–R1464
- . Transport of antiviral 3′-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes. Mol Membr Biol. 2001;18(2):161–167
- Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). J Biol Chem. 2001;276(4):2914–2927
- . Rat multispecific organic anion transporter 1(rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs. J Pharmacol Exp Ther. 2001;294(3):844–849
- . Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies. Drug Metab Pharmacokinet. 2005;20(6):452–477
- . The presence of xenobiotic transporters in rat placenta. Drug Metab Dispos. 2003;31(2):153–167
- . Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine. J Biol Chem. 2000;275(12):8375–8381
- Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues. J Biol Chem. 1997;272(45):28423–28430
- Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes. J Biol Chem. 2005;280(16):15880–15887
- . Identification and characterization of a novel monoamine transporter in the human brain. J Biol Chem. 2004;279(48):50042–50049
- . Adenosine transport and nitrobenzylthioinosine binding in human placental membrane vesicles from brush-border and basal sides of the trophoblast. J Membr Biol. 1991;119(2):151–161
- . Immunolocalisation of nucleoside transporters in human placental trophoblast and endothelial cells: evidence for multiple transporter isoforms. Pflugers Arch. 1995;429(3):394–399
- In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta. Am J Physiol Regul Integr Comp Physiol. 2007;293(5):R1809–R1822
- . Na+-dependent purine nucleoside transporter from human kidney: cloning and functional characterization. Am J Physiol. 1997;273(6 Pt 2):F1058–F1065
- . Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine. Mol Membr Biol. 1998;15(4):203–211
- Polarized glucose transporters and mRNA expression properties in newly developed rat syncytiotrophoblast cell lines, TR-TBTs. J Cell Physiol. 2002;193(2):208–218
- Conditionally immortalized syncytiotrophoblast cell lines as new tools for study of the blood–placenta barrier. Biol Pharm Bull. 2004;27(6):753–759
- . The expression of insulin-like growth factor (IGF) and IGF-binding protein (IGFBP) genes in the human placenta and membranes: evidence for IGF-IGFBP interactions at the feto-maternal interface. J Clin Endocrinol Metab. 1996;81(7):2680–2693
- Immunolocalization of GLUT1 and connexin 26 in the rat placenta. Cell Tissue Res. 1996;285(1):83–89
- . Glucose transporter GLUT3 in the rat placental barrier: a possible machinery for the transplacental transfer of glucose. Endocrinology. 1997;138(9):3997–4004
- . Potential of various drugs to inhibit nucleoside uptake in rat syncytiotrophoblast cell line, TR-TBT 18d-1. Placenta. 2008;29(5):461–467
- Characterization of the mechanism of zidovudine uptake by rat conditionally immortalized syncytiotrophoblast cell line TR-TBT. Pharm Res. 2008;25(7):1647–1653
- . Transport and metabolism of adenosine in the perfused human placenta. Placenta. 1995;16(7):611–622
- Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem Biophys Res Commun. 2000;273(1):251–260
- . Nucleoside transport at the blood-testis barrier studied with primary-cultured sertoli cells. J Pharmacol Exp Ther. 2005;312(2):601–608
- . In vivo evidence for carrier-mediated efflux transport of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine across the blood-brain barrier via a probenecid-sensitive transport system. J Pharmacol Exp Ther. 1997;281(1):369–375
- . Mechanisms by which 2′,3′-dideoxyinosine (ddI) crosses the guinea-pig CNS barriers; relevance to HIV therapy. J Neurochem. 2003;84(4):725–734
- Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2. Drug Metab Dispos. 2006;34(1):12–15
- . Mammalian nucleoside transporters. Curr Drug Metab. 2004;5(1):63–84
- Cell entry and export of nucleoside analogues. Virus Res. 2005;107(2):151–164
- Enhanced uptake of zidovudine with dehydroepiandrosterone sulfate in rat syncytiotrophoblast cell line TR-TBT 18d-1. Drug Metab Dispos. 2008;36(10):2080–2085
PII: S0143-4004(08)00397-4
doi: 10.1016/j.placenta.2008.11.022
© 2008 Elsevier Ltd. All rights reserved.
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Placenta
Volume 30, Issue 3
, Pages 263-269
, March 2009
