Placenta
Volume 30, Issue 7 , Pages 579-584 , July 2009

Endocannabinoid System and Nitric Oxide are Involved in the Deleterious Effects of Lipopolysaccharide on Murine Decidua

,Accepted 2 April 2009.

References 

  1. Sladek SM, Magness RR, Kirk PC. Nitric oxide and pregnancy. Am J Phys. 1997;272:441–463
  2. Chwalisz K, Winterhager E, Thienel T, Garfield RE. Synergistic role of nitric oxide and progesterone during the establishment of pregnancy in the rat. Hum Reprod. 1999;14:542–552
  3. Chwalisz K, Garfield RE. Role of nitric oxide in implantation and menstruation. Hum Reprod. 2000;15:96–111
  4. Grisham MB, Jourd'heuil D, Wink DA. Nitric oxide I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation. Am J Physiol. 1999;276:315–321
  5. Ogando DG, Paz D, Cella M, Franchi AM. The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice. Reproduction. 2003;125:95–110
  6. Aisemberg J, Vercelli C, Billi S, Ribeiro ML, Ogando D, Meiss R, et al. Nitric oxide mediates prostaglandin deleterious effect on lipopolysaccharide-triggered murine fetal resorption. Proc Natl Acad Sci USA. 2007;104:7534–7539
  7. Devane W, Hanus L, Breuer A, Pertwee R, Stevenson L, Griffin G, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 1992;258:1946–1949
  8. Mechoulam R, Fride E, Di Marzo V. Endocannabinoids. Eur J Pharmacol. 1998;359:1–18
  9. Di Marzo V, Bisogno T, De Petrocellis L, Melck D, Martín BR. Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. Curr Med Chem. 1999;6:721–744
  10. Paria BC, Deutsch DD, Dey SK. The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. Mol Rep Dev. 1996;45::183–19
  11. Schmid PC, Paria BC, Krebsbach RJ, Schmid HH, Dey SK. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. Proc Natl Acad Sci USA. 1997;94(8):4188–4192
  12. Liu J, Bátkai S, Pacher P, Harvey-White J, Wagner JA, Cravatt BF, et al. Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/Phosphoinositide 3-Kinase/NF-kB independently of platelet-activating factor. J Biol Chem. 2003;278(45):45034–450397
  13. Vercelli CA, Aisemberg J, Billi S, Cervini M, Ribeiro ML, Farina M, et al. Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in murine uterus. RBM Online. In press.
  14. Cella M, Leguizamón GF, Sordelli M, Cervini M, Guadagnoli T, Ribeiro ML, et al. Dual effect of anandamide on rat placenta nitric oxide synthesis. Placenta. 2008;29(8):699–707
  15. Grisham MB, Johnson GG, Lancaster JR. Quantification of nitrate and nitrite in extracellular fluids. Methods Enzymol. 1996;268:237–246
  16. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248–254
  17. Franchi A, Billi S, Cella M. Regulation of anandamide synthesis and cannabinoid receptors (CB1/CB2) expression during pregnancy in the mouse uterus. 2005 Symposium on the Cannabinoids, Burlington, Vermont, International Cannabinoid Research Society; 2005. p. 171.
  18. Guo Y, Wang H, Okamoto Y, Ueda N, Kingsley PJ, Marnett LJ, et al. N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation. J Biol Chem. 2005;280(25):23429–23432
  19. Bisogno T, Maurelli S, Melck D, De Petrocellis L, Di Marzo V. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. J Biol Chem. 1997;272:3315–3323
  20. Deutsch DG, Goligorsky MS, Schmid PC, Krebsbach RJ, Schmid HHO, Das SK, et al. Production and physiological actions of anandamide in the vasculature of the rat kidney. J Clin Invest. 1997;100:1538–1546
  21. Varga K, Wagner JA, Troy Bridgen D, Kunos G. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J. 1998;12:1035–1044
  22. Maccarrone M, Bari M, Lorenzon T, Bisogno T, Di Marzo V, Finazzi-Agrò A. Anandamide uptake by human endothelial cells and its regulation by nitric oxide. J Biol Chem. 2000;275(18):13484–13492
  23. Maccarrone M, De Petrocellis L, Bari M, Fezza F, Salvati S, Di Marzo V, et al. Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. Arch Biochem Biophys. 2001;393(2):321–328
  24. Sancho R, Calzado M, Di Marzo V, Appendino G, Muñoz E. Anandamide inhibits nuclear factor-κB activation through a cannabinoid receptor-independent pathway. Mol Pharmacol. 2003;63:429–438
  25. D'Argenio G, Valenti M, Scaglione G, Cosenza V, Sorrentini I, Di Marzo V. Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. FASEB J. 2006;express article 10.1096/fj.05–4943fje

PII: S0143-4004(09)00114-3

doi: 10.1016/j.placenta.2009.04.003

Placenta
Volume 30, Issue 7 , Pages 579-584 , July 2009