Placenta
Volume 31, Issue 3 , Pages 203-212 , March 2010

Mesenchymal stem cells in human placental chorionic villi reside in a vascular Niche

  • N.M. Castrechini

      Affiliations

    • Pregnancy Research Centre, Department of Perinatal Medicine, The Royal Women's Hospital Locked Bag 300, Cnr. Grattan St. and Flemington Rd., Parkville, Victoria 3052, Australia
    • Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria 3052, Australia
    • ,
  • P. Murthi

      Affiliations

    • Pregnancy Research Centre, Department of Perinatal Medicine, The Royal Women's Hospital Locked Bag 300, Cnr. Grattan St. and Flemington Rd., Parkville, Victoria 3052, Australia
    • Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria 3052, Australia
    • ,
  • N.M. Gude

      Affiliations

    • Pregnancy Research Centre, Department of Perinatal Medicine, The Royal Women's Hospital Locked Bag 300, Cnr. Grattan St. and Flemington Rd., Parkville, Victoria 3052, Australia
    • Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria 3052, Australia
    • ,
  • J.J.H.M. Erwich

      Affiliations

    • Department of Obstetrics and Gynaecology, University Medical Centre Groningen, PO BOX 30001, 9700 RB Groningen, The Netherlands
    • ,
  • S. Gronthos

      Affiliations

    • Division of Haematology, Institute of Medical and Veterinary Science/ Hanson Institute, Adelaide 5000, SA, Australia
    • ,
  • A. Zannettino

      Affiliations

    • Division of Haematology, Institute of Medical and Veterinary Science/ Hanson Institute, Adelaide 5000, SA, Australia
    • ,
  • S.P. Brennecke

      Affiliations

    • Pregnancy Research Centre, Department of Perinatal Medicine, The Royal Women's Hospital Locked Bag 300, Cnr. Grattan St. and Flemington Rd., Parkville, Victoria 3052, Australia
    • Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria 3052, Australia
    • ,
  • B. Kalionis

      Affiliations

    • Pregnancy Research Centre, Department of Perinatal Medicine, The Royal Women's Hospital Locked Bag 300, Cnr. Grattan St. and Flemington Rd., Parkville, Victoria 3052, Australia
    • Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria 3052, Australia
    • Corresponding Author InformationCorresponding author. Department of Perinatal Medicine, The Royal Women's Hospital Locked Bag 300, Cnr. Grattan St. and Flemington Rd., Parkville, Victoria 3052, Australia. Tel.: +61 3 83453748; fax: +61 3 83453746.

,Accepted 8 December 2009.

References 

  1. Fukuchi Y, Nakajima H, Sugiyama D, Hirose I, Kitamura T, Tsuji K. Human placenta-derived cells have mesenchymal stem/progenitor cell potential. Stem Cells. 2004;22:649–658
  2. Chien CC, Yen BL, Lee FK, Lai TH, Chen YC, Chan SH, et al. In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells. Stem Cells. 2006;24:1759–1768
  3. Wulf GG, Viereck V, Hemmerlein B, Haase D, Vehmeyer K, Pukrop T, et al. Mesengenic progenitor cells derived from human placenta. Tissue Eng. 2004;10:1136–1147
  4. Igura K, Zhang X, Takahashi K, Mitsuru A, Yamaguchi S, Takashi TA. Isolation and characterization of mesenchymal progenitor cells from chorionic villi of human placenta. Cytotherapy. 2004;6:543–553
  5. Zhang X, Mitsuru A, Igura K, Takahashi K, Ichinose S, Yamaguchi S, et al. Mesenchymal progenitor cells derived from chorionic villi of human placenta for cartilage tissue engineering. Biochem Biophys Res Commun. 2006;340:944–952
  6. Li CD, Zhang WY, Li HL, Jiang XX, Zhang Y, Tang P, et al. Isolation and identification of a multilineage potential mesenchymal cell from human placenta. Placenta. 2005;
  7. Miao Z, Jin J, Chen L, Zhu J, Huang W, Zhao J, et al. Isolation of mesenchymal stem cells from human placenta: comparison with human bone marrow mesenchymal stem cells. Cell Biol Int. 2006;30:681–687
  8. Li D, Wang GY, Dong BH, Zhang YC, Wang YX, Sun BC. Biological characteristics of human placental mesenchymal stem cells and their proliferative response to various cytokines. Cells Tissues Organs. 2007;186:169–179
  9. Chang CM, Kao CL, Chang YL, Yang MJ, Chen YC, Sung BL, et al. Placenta-derived multipotent stem cells induced to differentiate into insulin-positive cells. Biochem Biophys Res Commun. 2007;357:414–420
  10. Battula VL, Bareiss PM, Treml S, Conrad S, Albert I, Hojak S, et al. Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation. Differentiation. 2007;75:279–291
  11. Portmann-Lanz CB, Schoeberlein A, Huber A, Sager R, Malek A, Holzgreve W, et al. Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration. Am J Obstet Gynecol. 2006;194:664–673
  12. Fuchs E, Tumbar T, Guasch G. Socializing with the neighbors: stem cells and their niche. Cell. 2004;116:769–778
  13. Jones DL, Wagers AJ. No place like home: anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol. 2008;9:11–21
  14. Scadden DT. The stem-cell niche as an entity of action. Nature. 2006;441:1075–1079
  15. Shi S, Gronthos S. Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J Bone Miner Res. 2003;18:696–704
  16. Miura M, Gronthos S, Zhao M, Lu B, Fisher LW, Robey PG, et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA. 2003;100:5807–5812
  17. Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet. 2004;364:149–155
  18. Zannettino AC, Paton S, Arthur A, Khor F, Itescu S, Gimble JM, et al. Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. J Cell Physiol. 2008;214:413–421
  19. Garcia-Pacheco JM, Oliver C, Kimatrai M, Blanco FJ, Olivares EG. Human decidual stromal cells express CD34 and STRO-1 and are related to bone marrow stromal precursors. Mol Hum Reprod. 2001;7:1151–1157
  20. Zannettino AC, Paton S, Kortesidis A, Khor F, Itescu S, Gronthos S. Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45(-)/glycophorin-A-bone marrow cells. Haematologica. 2007;92:1707–1708
  21. Bensidhoum M, Chapel A, Francois S, Demarquay C, Mazurier C, Fouillard L, et al. Homing of in vitro expanded Stro-1− or Stro-1+ human mesenchymal stem cells into the NOD/SCID mouse and their role in supporting human CD34 cell engraftment. Blood. 2004;103:3313–3319
  22. Simmons PJ, Torok-Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 1991;78:55–62
  23. Owen M. Marrow stromal stem cells. J Cell Sci Suppl. 1988;10:63–76
  24. Rider DA, Nalathamby T, Nurcombe V, Cool SM. Selection using the alpha-1 integrin (CD49a) enhances the multipotentiality of the mesenchymal stem cell population from heterogeneous bone marrow stromal cells. J Mol Histol. 2007;38:449–458
  25. Deschaseaux F, Gindraux F, Saadi R, Obert L, Chalmers D, Herve P. Direct selection of human bone marrow mesenchymal stem cells using an anti-CD49a antibody reveals their CD45med, low phenotype. Br J Haematol. 2003;122:506–517
  26. Murthi P, Doherty V, Said J, Donath S, Brennecke SP, Kalionis B. Homeobox gene HLX1 expression is decreased in idiopathic human fetal growth restriction. Am J Pathol. 2006;168:511–518
  27. Mueller UW, Hawes CS, Jones WR. Identification of extra-villous trophoblast cells in human decidua using an apparently unique murine monoclonal antibody to trophoblast. Histochem J. 1987;19:288–296
  28. Hawes CS, Petropoulos A, Lopata A, Kalionis B, Jones WR. Reactivity of human trophoblast monoclonal antibodies with marmoset monkey trophoblast cultures. Hum Reprod. 1998;13:1169–1174
  29. Gronthos S, Zannettino AC, Hay SJ, Shi S, Graves SE, Kortesidis A, et al. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. J Cell Sci. 2003;116:1827–1835
  30. Strakova Z, Livak M, Krezalek M, Ihnatovych I. Multipotent properties of myofibroblast cells derived from human placenta. Cell Tissue Res. 2008;
  31. Yoshimura K, Shigeura T, Matsumoto D, Sato T, Takaki Y, Aiba-Kojima E, et al. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J Cell Physiol. 2006;208:64–76
  32. Aboagye-Mathiesen G, Laugesen J, Zdravkovic M, Ebbesen P. Isolation and characterization of human placental trophoblast subpopulations from first-trimester chorionic villi. Clin Diagn Lab Immunol. 1996;3:14–22
  33. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA. 2000;97:13625–13630
  34. Battula VL, Treml S, Abele H, Buhring HJ. Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody. Differentiation. 2008;76:326–336
  35. da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci. 2006;119:2204–2213
  36. Anderson DR, Davis EB. Glaucoma, capillaries and pericytes. 2. Identification and characterization of retinal pericytes in culture. Ophthalmologica. 1996;210:263–268
  37. Nayak RC, Berman AB, George KL, Eisenbarth GS, King GL. A monoclonal antibody (3G5)-defined ganglioside antigen is expressed on the cell surface of microvascular pericytes. J Exp Med. 1988;167:1003–1015
  38. Doherty MJ, Ashton BA, Walsh S, Beresford JN, Grant ME, Canfield AE. Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone Miner Res. 1998;13:828–838
  39. Richardson RL, Hausman GJ, Campion DR. Response of pericytes to thermal lesion in the inguinal fat pad of 10-day-old rats. Acta Anat (Basel. 1982;114:41–57
  40. Diaz-Flores L, Gutierrez R, Lopez-Alonso A, Gonzalez R, Varela H. Pericytes as a supplementary source of osteoblasts in periosteal osteogenesis. Clin Orthop Relat Res. 1992;280–286
  41. Bianco P, Riminucci M, Gronthos S, Robey PG. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells. 2001;19:180–192
  42. Farrington-Rock C, Crofts NJ, Doherty MJ, Ashton BA, Griffin-Jones C, Canfield AE. Chondrogenic and adipogenic potential of microvascular pericytes. Circulation. 2004;110:2226–2232
  43. Ohlsson R, Falck P, Hellstrom M, Lindahl P, Bostrom H, Franklin G, et al. PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta. Dev Biol. 1999;212:124–136
  44. Thomas D, Sunters A, Gentry A, Agamemnon E. Inhibition of chondrocyte differentiation in vitro by constitutive and inducible overexpression of the c-fos proto-oncogene. J Cell Sci. 2000;113:439–450
  45. Schwab KE, Gargett CE. Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium. Hum Repro. 2007;22:2903–2911

PII: S0143-4004(09)00396-8

doi: 10.1016/j.placenta.2009.12.006

Placenta
Volume 31, Issue 3 , Pages 203-212 , March 2010

Article Tools

* Image Usage & Resolution