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Volume 31, Issue 3 , Pages 245-248 , March 2010

Comparison of Phospholipid Molecular Species between Terminal and Stem Villi of Human Term Placenta by Imaging Mass Spectrometry

Y. Kobayashi
- Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan
- First two authors equally contributed to the study.
T. Hayasaka
- Department of Molecular Anatomy, Molecular Imaging Frontier Research Center, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan
- First two authors equally contributed to the study.
M. Setou
- Department of Molecular Anatomy, Molecular Imaging Frontier Research Center, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan
H. Itoh
- Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan
- Corresponding author. Tel.: +81 53 435 2309; fax: +81 53 435 2308.
N. Kanayama
- Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan

,Accepted 29 December 2009.

Photos of a section with a white square indicating the area imaged (B), hematoxylin and eosin staining of a nearby section (C) and the averaged mass spectrum from the area (A). Imaging results for m/z

Photos of a section with a white square indicating the area imaged (B), hematoxylin and eosin staining of a nearby section (C) and the averaged mass spectrum from the area (A). Imaging results for m/z 725.6 (D) and m/z 804.7 (E). These peaks were analyzed by direct MS/MS and identified as fragment ions of sphingomyelin (d18:1/16:0) (F) and phosphatidylcholine (16:0/20:4), respectively (G).
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