Placenta
Volume 31 , Pages S27-S32 , March 2010

Review: Sex Chromosome Evolution and the Expression of Sex-Specific Genes in the Placenta

  • J.A.M. Graves

      Affiliations

    • Corresponding Author InformationTel.: +61 2 6125 2492; fax: +61 2 6125 8525.

,Accepted 23 December 2009.

References 

  1. Renfree MB, Hore TA, Shaw G, Pask AJ, Graves JAM. Evolution of genomic imprinting: insights from marsupials and monotremes. Ann Rev Genomics Hum Genet. 2009;10:241–262
  2. Graves JAM. Genomic Imprinting, development and disease – is pre-eclampsia caused by an imprinted gene?. Reprod Fertil Dev. 1998;10:23–29
  3. Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, Cordum HS, Hillier L, Brown LG, et al. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature. 2003;423:825–837
  4. Graves JAM. Sex chromosome dynamics and Y chromosome degeneration. Cell. 2006;124:901–914
  5. Lahn B, Page DC. Functional coherence of the human Y chromosome. Science. 1997;278:675–680
  6. Sinclair AH, Berta P, Palmer MS, Hawkins JR, Griffiths BL, Smith MJ, et al. A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature. 1990;346:240–244
  7. Graves JAM. Weird animal genomes and the evolution of sex and sex chromosomes. Annu Rev Genet. 2008;42:565–586
  8. Ohno S. Sex chromosomes and sex linked genes. New York: Springer-Verlag; 1967;
  9. Rodriguez Delgado CL, Waters PD, Gilbert C, Robinson TJ, Graves JAM. Physical Mapping of the Elephant X chromosome conservation of gene order over 105 million years. Chromosome Res. 2009;17:917–926
  10. Charlesworth B, Charlesworth D. The degeneration of Y chromosomes. Philos Trans R Soc Lond Ser B. 2000;355:1563–1572
  11. Graves JAM. The origin and function of the mammalian Y chromosome and Y-borne genes- an evolving understanding. Bioessays. 1995;17:311–320
  12. Graves JAM. From brain-determination to testis-determination: evolution of the mammalian sex determining gene. Reprod Fertil Dev. 2001;13:1–8
  13. Fisher RA. The evolution of dominance. Biol Rev. 1931;6:345–368
  14. Li WH, Yi S, Makova K. Male-driven evolution. Curr Opin Genet Dev. 2002 Dec;12(6):650–656
  15. Guo X, Su B, Zhou Z, Sha J. Rapid evolution of mammalian X-linked testis microRNAs. BMC Genomics. 2009 Mar 4;10:97
  16. Ishibashi T, Li A, Eirín-López JM, Zhao M, Missiaen K, Abbott DW, Meistrich M, Hendzel MJ, Ausió J. H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis. Nucleic Acids Res…[Epub ahead of print]
  17. Simpson AJ, Caballero OL, Jungbluth A, Chen YT, Old LJ. Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer. 2005;5:615–625
  18. Lyon MF. Gene action in the X chromosome of the mouse (Mus musculus L.). Nature. 1961;190:372–373
  19. Graves JAM, Gartler SM. Mammalian X chromosome inactivation; testing the hypothesis of transcriptional control. Somat Cell Molec Genet. 1986;12:275–280
  20. Heard E, Disteche CM. Dosage compensation in mammals: fine-tuning the expression of the X chromosome. Genes Dev. 2006;20:1848–1867
  21. Brown CJ, Hendrich BD, Rupert JL, Lafreniere RG, Xing Y, Lawrence J, et al. The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell. 1992;71:527–542
  22. Carrel L, Willard HF. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature. 2005 Mar 17;434(7031):400–404
  23. Migeon BR. Females are mosaics. Oxford: Oxford University Press; 2007;
  24. Cooper DW, Johnston PG, Graves JAM, Watson JM. X-inactivation in marsupials and monotremes. Sem Dev Biol. 1993;4:117–128
  25. Hore T, Rapkins RE, Graves JAM. Evolutionary timing of genomic imprinting and X inactivation in mammals. Trends Genet. 2007;23:440–448
  26. Koina E, Chaumeil J, Greaves IK, Tremethick DJ, Graves JAM. Loss of active histone marks accompany X chromosome inactivation in a marsupial. Chromosome Res. 2009;17:115–126
  27. Wolf U. The serologically detected H-Y antigen revisited. Cytogenet Cell Genet. 1998;80(1–4):232–235
  28. Simpson E. The case of the midwife scientist. Int J Dev Biol. 2001;45(3):513–518
  29. Scott DM, Ehrmann IE, Ellis PS, Chandler PR, Simpson E. Why do some females reject males? The molecular basis for male-specific graft rejection. J Mol Med. 1997;75(2):103–114
  30. Warren EH, Gavin MA, Simpson E, Chandler P, Page DC, Disteche C, et al. The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen. J Immunol. 2000;164(5):2807–2814
  31. Vogt MH, van den Muijsenberg JW, Goulmy E, Spierings E, Kluck P, Kester MG, et al. The DBY gene codes for an HLA-DQ5-restricted human male-specific minor histocompatibility antigen involved in graft-versus-host disease. Blood. 2002;99(8):3027–3032
  32. Millrain M, Scott D, Addey C, Dewchand H, Ellis P, Ehrmann I, et al. Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses. J Immunol. 2005;175(11):7209–7217
  33. Kim SJ, Gill JS. H-Y compatibility predicts short-term outcomes for kidney transplant recipients. J Am Soc Nephrol. 2009;20(9):2025–2033
  34. Tan JC, Wadia PP, Coram M, Grumet FC, Kambham N, Miller K, et al. H-Y antibody development associates with acute rejection in female patients with male kidney transplants. Transplantation. 2008;86(1):75–81
  35. Dierselhuis M, Goulmy E. The relevance of minor histocompatibility antigens in solid organ transplantation. Curr Opin Organ Transpl. 2009;14(4):419–425
  36. Nielsen HS, Steffensen R, Varming K, Van Halteren AG, Spierings E, Ryder LP, et al. Association of HY-restricting HLA class II alleles with pregnancy outcome in patients with recurrent miscarriage subsequent to a firstborn boy. Hum Mol Genet. 2009;18(9):1684–1691
  37. Bonney EA, Onyekwuluje J. The H-Y response in mid-gestation and long after delivery in mice primed before pregnancy. Immunol Invest. 2003;32(1–2):71–81
  38. Takagi N. Imprinted X-chromosome inactivation: enlightenment from embryos in vivo. Semin Cell Dev Biol. 2003;14(6):319–329
  39. Okamoto I, Heard E. The dynamics of imprinted X inactivation during preimplantation development in mice. Cytogenet Genome Res. 2006;113(1–4):318–324
  40. Huynh KD, Lee JT. Imprinted X inactivation in eutherians: a model of gametic execution and zygotic relaxation. Curr Opin Cell Biol. 2001;13(6):690–697
  41. Okamoto I, Otte AP, Allis CD, Reinberg D, Heard E. Epigenetic dynamics of imprinted X inactivation during early mouse development. Science. 2004;303(5658):644–649
  42. Mahadevaiah SK, Royo H, Vandeberg JL, McCarrey JR, Mackay S, Turner JM. Key features of the X inactivation process are conserved between marsupials and Euthians. Curr Biol. 2009;19(17):1478–1484
  43. Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T. Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009;460(7255):647–651
  44. Xue F, Tian XC, Du F, Kubota C, Taneja M, Dinnyes A, et al. Aberrant patterns of X chromosome inactivation in bovine clones. Nat Genet. 2002;31(2):216–220
  45. Harrison KB, Warburton D. Preferential X-chromosome activity in human female placental tissues. Cytogenet Cell Genet. 1986;41(3):163–168
  46. Goto T, Wright E, Monk M. Paternal X-chromosome inactivation in human trophoblastic cells. Mol Hum Reprod. 1997;3(1):77–80
  47. Mohandas TK, Passage MB, Williams JW, Sparkes RS, Yen PH, Shapiro LJ. X-chromosome inactivation in cultured cells from human chorionic villi. Somat Cell Mol Genet. 1989;15(2):131–136
  48. Uehara S, Tamura M, Nata M, Ji G, Yaegashi N, Okamura K, et al. X-chromosome inactivation in the human trophoblast of early pregnancy. J Hum Genet. 2000;45(3):119–126
  49. Zeng SM, Yankowitz J. X-inactivation patterns in human embryonic and extra-embryonic tissues. Placenta. 2003;24(2–3):270–275
  50. Migeon BR, Schmidt M, Axelman J, Cullen CR. Complete reactivation of X chromosomes from human chorionic villi with a switch to early DNA replication. Proc Natl Acad Sci USA. 1986;83(7):2182–2186
  51. Cotton AM, Avila L, Penaherrera MS, Affleck JG, Robinson WP, Brown CJ. Inactive X chromosome-specific reduction in placental DNA methylation. Hum Mol Genet. 2009;18(19):3544–3552
  52. Clifton VL. Sex and the Human Placenta: Mediating Differential Strategies of Fetal Growth and Survival. Placenta. [2009, Epub ahead of print].

PII: S0143-4004(10)00007-X

doi: 10.1016/j.placenta.2009.12.029

Placenta
Volume 31 , Pages S27-S32 , March 2010