Placenta
Volume 31 , Pages S54-S59 , March 2010

Review: The Placenta is a Programming Agent for Cardiovascular Disease

  • K.L. Thornburg

      Affiliations

    • Heart Research Center, Oregon Health & Science University, 3303 SW Bond Avenue, CH15H, Portland, OR 97239, USA
    • Department of Medicine (Division of Cardiovascular Medicine), Oregon Health & Science University, Portland, OR 97239, USA
    • Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR 97239, USA
    • Corresponding Author InformationCorresponding author at: Heart Research Center, Oregon Health & Science University, 3303 SW Bond Avenue, CH15H, Portland, OR 97239, USA. Tel.: +1 503 494 2382; fax: +1 503 494 6969.
    • ,
  • P.F. O'Tierney

      Affiliations

    • Heart Research Center, Oregon Health & Science University, 3303 SW Bond Avenue, CH15H, Portland, OR 97239, USA
    • ,
  • S. Louey

      Affiliations

    • Heart Research Center, Oregon Health & Science University, 3303 SW Bond Avenue, CH15H, Portland, OR 97239, USA
    • Department of Medicine (Division of Cardiovascular Medicine), Oregon Health & Science University, Portland, OR 97239, USA

,Accepted 4 January 2010.

  • Image Result

    Hypertension in offspring of short and tall mothers as a function of placental area. Incidence of hypertension according to placental area is divided based upon maternal height (black bars: <160 cm; w

    Hypertension in offspring of short and tall mothers as a function of placental area. Incidence of hypertension according to placental area is divided based upon maternal height (black bars: <160 cm; white bars: >160 cm). Individual bars represent placental area categories. There was a significant relationship between hypertension and placental area in offspring of short mothers (p < 0.002) but not tall mothers (p = 0.72). Data from Barker et al. [8].

  • Image Result
    Standardized mortality ratios (SMR) for coronary heart disease in adult offspring of short (<158cm) mothers, categorized according to maternal body mass index (BMI) at term. Data from Forsen et al. [6

    Standardized mortality ratios (SMR) for coronary heart disease in adult offspring of short (<158cm) mothers, categorized according to maternal body mass index (BMI) at term. Data from Forsen et al. [6].

PII: S0143-4004(10)00008-1

doi: 10.1016/j.placenta.2010.01.002

Placenta
Volume 31 , Pages S54-S59 , March 2010

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