Placenta
Volume 31, Issue 5 , Pages 460-462, May 2010

AMP-Deaminase from Developing Human Placenta

  • A. Swieca

      Affiliations

    • Department of Biochemistry and Clinical Physiology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland
    • ,
  • I. Rybakowska

      Affiliations

    • Department of Biochemistry and Clinical Physiology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland
    • Corresponding Author InformationCorresponding author. Tel./fax: +48 58 349 14 65.
    • ,
  • R. Milczarek

      Affiliations

    • Department of Pharmaceutical Biochemistry, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland
    • ,
  • J. Klimek

      Affiliations

    • Department of Pharmaceutical Biochemistry, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland
    • ,
  • K. Kaletha

      Affiliations

    • Department of Biochemistry and Clinical Physiology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland

Accepted 12 February 2010. published online 08 March 2010.

Abstract 

During pregnancy the activity of AMP-deaminase in developing human placenta gradually decreases, being in homogenates of mature, term placenta (∼40 week of gestation) one fourth to one third of that in homogenates of immature (∼25 week of gestation) organ. The gradual decrease of activity correlates inversely with the increasing presence of the form of enzyme predominating in homogenates of the mature placenta. The discrepancy observed indicate that isozymic pattern of AMP-deaminase in developing human placenta changes.

Keywords: AMP-deaminase, Human placenta, Pregnancy

 

PII: S0143-4004(10)00088-3

doi:10.1016/j.placenta.2010.02.009

Placenta
Volume 31, Issue 5 , Pages 460-462, May 2010

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