Placenta
Volume 31, Issue 9 , Pages 792-795 , September 2010

Histologic Chorioamnionitis is More Common after Spontaneous Labor than after Induced Labor at Term

  • H.S. Park

      Affiliations

    • Department of Obstetrics and Gynecology, Graduate School of Medicine, Dongguk University, Seoul, South Korea
    • ,
  • R. Romero

      Affiliations

    • Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, and Detroit, MI, USA
    • Department of Obstetrics and Gynecology and Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA
    • ,
  • S.M. Lee

      Affiliations

    • Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea
    • ,
  • C.W. Park

      Affiliations

    • Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea
    • ,
  • J.K. Jun

      Affiliations

    • Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea
    • ,
  • B.H. Yoon

      Affiliations

    • Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea
    • Corresponding Author InformationCorresponding author. Tel.: +82 2 760 2826; fax: +82 2 765 3002.

,Accepted 21 June 2010.

References 

  1. Hillier SL, Krohn MA, Kiviat NB, Watts DH, Eschenbach DA. Microbiologic causes and neonatal outcomes associated with chorioamnion infection. Am J Obstet Gynecol. 1991;165:955–961
  2. Hillier SL, Martius J, Krohn M, Kiviat N, Holmes KK, Eschenbach DA. A case-control study of chorioamnionic infection and histologic chorioamnionitis in prematurity. N Engl J Med. 1988;319:972–978
  3. Keski-Nisula L, Aalto ML, Katila ML, Kirkinen P. Intrauterine inflammation at term: a histopathologic study. Hum Pathol. 2000;31:841–846
  4. Seong HS, Lee SE, Kang JH, Romero R, Yoon BH. The frequency of microbial invasion of the amniotic cavity and histologic chorioamnionitis in women at term with intact membranes in the presence or absence of labor. Am J Obstet Gynecol. 2008;199(375):e371–375
  5. Wu YW, Colford JM. Chorioamnionitis as a risk factor for cerebral palsy: a meta-analysis. JAMA. 2000;284:1417–1424
  6. Wu YW, Escobar GJ, Grether JK, Croen LA, Greene JD, Newman TB. Chorioamnionitis and cerebral palsy in term and near-term infants. JAMA. 2003;290:2677–2684
  7. Lee J, Seong HS, Kim BJ, Jun JK, Romero R, Yoon BH. Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in “indicated” than in “spontaneous” preterm birth. J Perinat Med. 2009;37:53–58
  8. Yoon BH, Romero R, Kim CJ, Jun JK, Gomez R, Choi JH, et al. Amniotic fluid interleukin-6: a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity. Am J Obstet Gynecol. 1995;172:960–970
  9. Romero R, Espinoza J, Kusanovic JP, Gotsch F, Hassan S, Erez O, et al. The preterm parturition syndrome. BJOG. 2006;113(Suppl. 3):17–42
  10. Chaiworapongsa T, Erez O, Kusanovic JP, Vaisbuch E, Mazaki-Tovi S, Gotsch F, et al. Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition. J Matern Fetal Neonatal Med. 2008;21:449–461
  11. Gotsch F, Romero R, Kusanovic JP, Erez O, Espinoza J, Kim CJ, et al. The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: a role for interleukin-10. J Matern Fetal Neonatal Med. 2008;21:529–547
  12. Haddad R, Tromp G, Kuivaniemi H, Chaiworapongsa T, Kim YM, Mazor M, et al. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol. 2006;195(394):394.31–24
  13. Keelan JA, Marvin KW, Sato TA, Coleman M, McCowan LM, Mitchell MD. Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition. Am J Obstet Gynecol. 1999;181:1530–1536
  14. Mittal P, Romero R, Mazaki-Tovi S, Tromp G, Tarca AL, Kim YM, et al. Fetal membranes as an interface between inflammation and metabolism: increased aquaporin 9 expression in the presence of spontaneous labor at term and chorioamnionitis. J Matern Fetal Neonatal Med. 2009;22:1167–1175
  15. Thomson AJ, Telfer JF, Young A, Campbell S, Stewart CJ, Cameron IT, et al. Leukocytes infiltrate the myometrium during human parturition: further evidence that labour is an inflammatory process. Hum Reprod. 1999;14:229–236
  16. Hershkovitz R, Erez O, Sheiner E, Bashiri A, Furman B, Shoham-Vardi I, et al. Comparison study between induced and spontaneous term and preterm births of small-for-gestational-age neonates. Eur J Obstet Gynecol Reprod Biol. 2001;97:141–146
  17. Levey KA, MacKenzie AP, Stephenson C, Bercik R, Kuczynski E, Funai EF. Increased rates of chorioamnionitis with extra-amniotic saline infusion method of labor induction. Obstet Gynecol. 2004;103:724–728
  18. Yoon BH, Chang JW, Romero R. Isolation of ureaplasma urealyticum from the amniotic cavity and adverse outcome in preterm labor. Obstet Gynecol. 1998;92:77–82
  19. Yoon BH, Romero R, Lim JH, Shim SS, Hong JS, Shim JY, et al. The clinical significance of detecting ureaplasma urealyticum by the polymerase chain reaction in the amniotic fluid of patients with preterm labor. Am J Obstet Gynecol. 2003;189:919–924
  20. Yoon BH, Romero R, Moon JB, Shim SS, Kim M, Kim G, et al. Clinical significance of intra-amniotic inflammation in patients with preterm labor and intact membranes. Am J Obstet Gynecol. 2001;185:1130–1136
  21. Lee SE, Romero R, Kim CJ, Shim SS, Yoon BH. Funisitis in term pregnancy is associated with microbial invasion of the amniotic cavity and intra-amniotic inflammation. J Matern Fetal Neonatal Med. 2006;19:693–697
  22. Lee SM, Romero R, Lee KA, Yang HJ, Oh KJ, Park CW, et al. The frequency and risk factors of funisitis and histologic chorioamnionitis in term pregnant women delivered after the spontaneous onset of labor. J Matern Fetal Neonatal Med 2010, doi:10.3109/14767058.2010.482622.
  23. Grether JK, Nelson KB. Maternal infection and cerebral palsy in infants of normal birth weight. JAMA. 1997;278:207–211

PII: S0143-4004(10)00243-2

doi: 10.1016/j.placenta.2010.06.013

Placenta
Volume 31, Issue 9 , Pages 792-795 , September 2010

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