Placenta
Volume 31, Issue 10 , Pages 873-879 , October 2010

Anti-oxidative and anti-inflammatory activities of placental extracts in benzo[a]pyrene-exposed rats

  • S.Y. Park

      Affiliations

    • Department of Nanobiomedical Science, College of Advanced Science, Dankook University, Cheonan, South Korea
    • Joint first authors.
  • ,
  • S. Phark

      Affiliations

    • Graduate School of Medicine, Korea University, Seoul, South Korea
    • Joint first authors.
  • ,
  • M. Lee

      Affiliations

    • Graduate School of Medicine, Korea University, Seoul, South Korea
  • ,
  • J.Y. Lim

      Affiliations

    • Environmental Toxico-Genomic and Proteomic Center, College of Medicine, Korea University, Seoul, South Korea
  • ,
  • D. Sul

      Affiliations

    • Graduate School of Medicine, Korea University, Seoul, South Korea
    • Environmental Toxico-Genomic and Proteomic Center, College of Medicine, Korea University, Seoul, South Korea
    • Corresponding Author InformationCorresponding author. Graduate School of Medicine, Korea University, 126-1, Anam-Dong 5Ka, Seongbuk-Ku, Seoul, South Korea. Tel.: +82 2 920 6420; fax: +82 2 929 6420.

,Accepted 20 July 2010.

References 

  1. Tonello G, Daglio M, Zaccarelli N, Sottofattori E, Mazzei M, Balbi A. Characterization and quantitation of the active polynucleotide fraction (PDRN) from human placenta, a tissue repair stimulating agent. J Pharm Biomed Anal. 1996;14:1555–1560
  2. Biswas TK, Auddy B, Bhattacharya NP, Bhattacharya S, Mukherjee B. Wound healing activity of human placental extracts in rats. Acta Pharmacol Sin. 2001;22:1113–1116
  3. Watanabe S, Togashi S, Takahashi N, Fukui T. L-tryptophan as an antioxidant in human placenta extract. J Nutr Sci Vitaminol (Tokyo). 2002;48:36–39
  4. Togashi S, Takahashi N, Iwama M, Watanabe S, Tamagawa K, Fukui T. Antioxidative collagen-derived peptides in human-placenta extract. Placenta. 2002;23:497–502
  5. Oh E, Lee E, Im H, Kang HS, Jung WW, Won NH, et al. Evaluation of immuno- and reproductive toxicities and association between immunotoxicological and genotoxicological parameters in waste incineration workers. Toxicology. 2005;210:65–80
  6. Kim KB, Lee BM. Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo(a)pyrene. Cancer Lett. 1997;113:205–212
  7. Gelboin HV. Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. Physiol Rev. 1980;60:1107–1166
  8. Kim S, Hwang SK, Dwek RA, Rudd PM, Ahn YH, Kim EH, et al. Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein. Glycobiology. 2003;13:147–157
  9. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37:911–917
  10. Moir D, Viau A, Chu I, Withey J, McMullen E. Pharmacokinetics of benzo[a]pyrene in the rat. J Toxicol Environ Health A. 1998;53:507–530
  11. Park SY, Kim HS, Cho EK, Kwon BY, Phark S, Hwang KW, et al. Curcumin protected PC12 cells against beta-amyloid-induced toxicity through the inhibition of oxidative damage and tau hyperphosphorylation. Food Chem Toxicol. 2008;46:2881–2887
  12. Moore K, Roberts LJ. Measurement of lipid peroxidation. Free Radic Res. 1998;28(6):659–671
  13. Seljeskog E, Hervig T, Mansoor MA. A novel HPLC method for the measurement of thiobarbituric acid reactive substances (TBARS). A comparison with a commercially available kit. Clin Biochem. 2006;39:947–954
  14. Nakayama S, Kodama K, Oguchi K. A comparative study of human placenta hydrolysate (Laennec) by intravenous or subcutaneous injection on liver regeneration after partial hepatectomy in normal and CCl4-induced cirrhosis rats. Nippon Yakurigaku Zasshi. 1989;94:289–297
  15. Liu KX, Kato Y, Kaku T, Sugiyama Y. Human placental extract stimulates liver regeneration in rats. Biol Pharm Bull. 1998;21:44–49
  16. Kong MH, Lee EJ, Lee SY, Cho SJ, Hong YS, Park SB. Effect of human placental extract on menopausal symptoms, fatigue, and risk factors for cardiovascular disease in middle-aged Korean women. Menopause. 2008;15:296–303
  17. Fang XP, Xia WS, Sheng QH, Wang YL. Purification and characterization of an immunomodulatory peptide from bovine placenta water-soluble extract. Prep Biochem Biotechnol. 2007;37:173–184
  18. Chakraborty PD, Bhattacharyya D. Isolation of fibronectin type III like peptide from human placental extract used as wound healer. J Chromatogr B Analyt Technol Biomed Life Sci. 2005;818:67–73
  19. Udintsev NA, Ivanov VV. Antioxidant action of glutamic acid. Patol Fiziol Eksp Ter. 1984;4:60–62
  20. Liu DZ, Lin YS, Hou WC. Monohydroxamates of aspartic acid and glutamic acid exhibit antioxidant and angiotensin converting enzyme inhibitory activities. J Agric Food Chem. 2004;52:2386–2390
  21. Rajapakse AG, Ming XF, Carvas JM, Yang Z. O-linked beta-N-acetylglucosamine during hyperglycemia exerts both anti-inflammatory and pro-oxidative properties in the endothelial system. Oxid Med Cell Longev. 2009;2:172–175
  22. Singh S, Khajuria A, Taneja SC, Khajuria RK, Singh J, Qazi GN. Boswellic acids and glucosamine show synergistic effect in preclinical anti-inflammatory study in rats. Bioorg Med Chem Lett. 2007;17:3706–3711
  23. Yokoyama T, Yamane K, Minamoto A, Tsukamoto H, Yamashita H, Izumi S, et al. High glucose concentration induces elevated expression of anti-oxidant and proteolytic enzymes in cultured human retinal pigment epithelial cells. Exp Eye Res. 2006;83:602–609
  24. Oikawa S, Kawanishi S. Distinct mechanisms of site-specific DNA damage induced by endogenous reductants in the presence of iron(III) and copper(II). Biochim Biophys Acta. 1998;1399:19–30
  25. Skouroliakou M, Konstantinou D, Koutri K, Kakavelaki C, Stathopoulou M, Antoniadi M, et al. A double-blind, randomized clinical trial of the effect of omega-3 fatty acids on the oxidative stress of preterm neonates fed through parenteral nutrition. Eur J Clin Nutr, in press, doi:10.1038/ejcn.2100.98.
  26. Tiesset H, Pierre M, Desseyn JL, Guéry B, Beermann C, Galabert C, et al. Dietary (n-3) polyunsaturated fatty acids affect the kinetics of pro- and antiinflammatory responses in mice with Pseudomonas aeruginosa lung infection. J Nutr. 2009;139:82–89
  27. Kim JH, Stansbury KH, Walker NJ, Trush MA, Strickland PT, Sutter TR. Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1. Carcinogenesis. 1998;19:1847–1853
  28. Marshall CJ, Vousden KH, Phillips DH. Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide. Nature. 1984;310:586–589
  29. Rundle A, Tang D, Hibshoosh H, Estabrook A, Schnabel F, Cao W, et al. The relationship between genetic damage from polycyclic aromatic hydrocarbons in breast tissue and breast cancer. Carcinogenesis. 2000;21:1281–1289
  30. Conney AH. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G.H.A. Clowes Memorial lecture. Cancer Res. 1982;42:4875–4917
  31. Lorentzen RJ, Ts’o PO. Benzo[a]yrenedione/benzo[a]pyrenediol oxidation-reduction couples and the generation of reactive reduced molecular oxygen. Biochemistry. 1977;16:1467–1473
  32. Bolton JL, Trush MA, Penning TM, Dryhurst G, Monks TJ. Role of quinones in toxicology. Chem Res Toxicol. 2000;13:135–160
  33. Yusuf AT, Vian L, Sabatier R, Cano JP. In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells. Mutat Res. 2000;468:227–234
  34. Binelli A, Riva C, Cogni D, Provini A. Assessment of the genotoxic potential of benzo(a)pyrene and pp′-dichlorodiphenyldichloroethylene in Zebra mussel (Dreissena polymorpha). Mutat Res. 2008;649:135–145
  35. Nwagbara O, Darling-Reed SF, Tucker A, Harris C, Abazinge M, Thomas RD, et al. Induction of cell death, DNA strand breaks, and cell cycle arrest in DU145 human prostate carcinoma cell line by benzo[a]pyrene and benzo[a]pyrene-7,8-diol-9,10-epoxide. Int J Environ Res Public Health. 2007;4:10–14
  36. Garry S, Nesslany F, Aliouat E, Haguenoer JM, Marzin D. Assessment of genotoxic effect of benzo[a]pyrene in endotracheally treated rat using the comet assay. Mutat Res. 2003;534:33–43
  37. Szczeklik A, Szczeklik J, Galuszka Z, Musial J, Kolarzyk E, Targosz D. Humoral immunosuppression in men exposed to polycyclic aromatic hydrocarbons and related carcinogens in polluted environments. Environ Health Perspect. 1994;102:302–304
  38. Winker N, Tuschl H, Kovac R, Weber E. Immunological investigations in a group of workers exposed to various levels of polycyclic aromatic hydrocarbons. J Appl Toxicol. 1997;17:23–29
  39. Lyte M, Bick PH. Modulation of interleukin-1 production by macrophages following benzo(a)pyrene exposure. Int J Immunopharmacol. 1986;8:377–381
  40. Garcon G, Campion J, Hannothiaux MH, Boutin AC, Venembre P, Balduyck M, et al. Modification of the proteinase/anti-proteinase balance in the respiratory tract of Sprague–Dawley rats after single intratracheal instillation of benzo[A]pyrene-coated onto Fe(2)O(3) particles. J Appl Toxicol. 2000;20:265–271
  41. Lecureur V, Ferrec EL, N’Diaye M, Vee ML, Gardyn C, Gilot D, et al. ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages. FEBS Lett. 2005;579:1904–1910
  42. Chin BY, Choi ME, Burdick MD, Strieter RM, Risby TH, Choi AM. Induction of apoptosis by particulate matter: role of TNF-alpha and MAPK. Am J Physiol. 1998;275:L942–L949
  43. Kankofer M. Antioxidative defence mechanisms against reactive oxygen species in bovine retained and not-retained placenta: activity of glutathione peroxidase, glutathione transferase, catalase and superoxide dismutase. Placenta. 2001;22:466–472
  44. Mochizuki H, Kada T. Antimutagenic action of mammalian placental extracts on mutations induced in Escherichia coli by UV radiation, gamma-rays and N-methyl-N′-nitro-N-nitrosoguanidine. Mutat Res. 1982;95:457–474
  45. Sur TK, Biswas TK, Ali L, Mukherjee B. Anti-inflammatory and anti-platelet aggregation activity of human placental extract. Acta Pharmacol Sin. 2003;24:187–192

PII: S0143-4004(10)00279-1

doi: 10.1016/j.placenta.2010.07.010

Placenta
Volume 31, Issue 10 , Pages 873-879 , October 2010