Placenta
Volume 33, Issue 2 , Pages 124-127, February 2012

Impact of genetic background on placental glycogen storage in mice

Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, CF10 3AX, UK

Accepted 18 November 2011. published online 09 December 2011.

Abstract 

129 and C57BL/6 are two of the most widely used laboratory mouse strains. While it is well known that genetic modifiers between the two strains can directly influence embryonic and adult phenotypes, less is known regarding morphological differences in placental development. Here we identify differences in the junctional zone, glycogen storage and the maternal-fetal interface between these two strains and provide examples where these differences impact the phenotypic characterisation of placental mutations.

Keywords: Placenta glycogen, Genetic background

Abbreviations: Jz, Junctional zone, Lz, Labyrinth zone, PAS, Periodic acid-Schiff

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PII: S0143-4004(11)00543-1

doi:10.1016/j.placenta.2011.11.011

Placenta
Volume 33, Issue 2 , Pages 124-127, February 2012

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